Evidence map›Paper›PMID 41907206›Full record

ArticleJournal of inflammation research2026

ANCA-Associated Vasculitis with Predominant Peripheral and Central Nervous System Involvement: A Case Report.

Bing Zhang, Chaoyang Jing, Peipei Liu, Jianlei Zhang

Abstract readCase Reports
In one paragraph

Article in Journal of inflammation research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bing ZhangDepartment of Neurology, Huaihe Hospital of Henan University, Kaifeng, Henan, 475000, People's Republic of China.ORCID 0009-0009-6257-5962
Chaoyang JingDepartment of Neurology, Huaihe Hospital of Henan University, Kaifeng, Henan, 475000, People's Republic of China.
Peipei LiuDepartment of Neurology, Huaihe Hospital of Henan University, Kaifeng, Henan, 475000, People's Republic of China.
Jianlei ZhangDepartment of Neurology, Huaihe Hospital of Henan University, Kaifeng, Henan, 475000, People's Republic of China.ORCID 0009-0003-8457-3278

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: ANCA-associated vasculitis (AAV) is an immune-mediated multi-system disease. It can present with neurological involvement as its predominant manifestation. We report a case of AAV with predominant peripheral and central nervous system involvement. Case Presentation: A 62-year-old male presented with fever and asymmetric weakness and pain in the lower limbs. Electrophysiological studies revealed asymmetric axonal damage in both lower limbs. During hospitalization, he developed acute bulbar palsy. Brain MRI confirmed bilateral basal ganglia infarction. Ancillary tests indicated involvement of the lungs, kidneys, and hematological systems, along with positive MPO-ANCA (p-ANCA), confirming the diagnosis of AAV. His symptoms gradually improved following treatment with glucocorticoids and immunosuppressants. At the 6-month follow-up, his symptoms were largely resolved. Conclusion: The presence of asymmetric axonal neuropathy or atypical non-atherosclerotic cerebral infarction, particularly when accompanied by multisystem involvement, should raise suspicion for AAV. Early diagnosis and prompt treatment significantly improve patient outcomes.

Indexed as

ANCA-associated vasculitiscentral nervous systemMPAperipheral neuropathy

Identifiers

PMID41907206
PMCPMC13032754

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.