Evidence map›Paper›PMID 41906842›Full record

ArticleJoint diseases and related surgery2026

Evaluating deepresearch and deepthink in total knee arthroplasty patient education: ChatGPT-4o excels in comprehensiveness, Deepseek R1 leads in clarity and readability of orthopedic information.

Onur Gultekin, Michael T Hirschmann, Halil İbrahim Arıkan, Bekir Eray Kilinc, Baris Yilmaz, Süleyman Abul, Jumpei Inoue, Mahmut Enes Kayaalp

Registry-linked trialAbstract readComparative Study
In one paragraph

Article in Joint diseases and related surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07631585 (Longitudinal Pre-Post Patient AI Trust Dynamics in Orthopedic Outpatients), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07631585 recruitingnot on this map

Longitudinal Pre-Post Patient AI Trust Dynamics in Orthopedic Outpatients: A Mixed-Methods Observational Study With Matched Physician-Patient Dyads

TypeobservationalSponsorUtku GürhanRan2026 to 2027Enrolled180ConditionsPatient Health Information Seeking Behavior, Trust, Health Literacy, Orthopedics
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Onur Gultekin
Michael T Hirschmann
Halil İbrahim Arıkan
Bekir Eray Kilinc
Baris Yilmaz
Süleyman Abul
Jumpei Inoue
Mahmut Enes KayaalpSBÜ İstanbul Fatih Sultan Mehmet Eğitim ve Araştırma Hastanesi, Ortopedi ve Travmatoloji Kliniği, 34752 Ataşehir, İstanbul, Türkiye. mek@mek.md.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aims to directly compare ChatGPT and DeepSeek, both equipped with DeepResearch/DeepThink capabilities, based on their responses to frequently asked questions (FAQs) on total knee arthroplasty (TKA). MATERIALS AND

methodsThirty frequently asked questions related to TKA were compiled from validated patient education sources, including American Academy of Orthopaedic Surgeons (AAOS) OrthoInfo, National Institute for Health and Care Excellence (NICE) guidelines, and popular patient discussion forums, and verified for clinical relevance by two independent arthroplasty surgeons. Two orthopedic surgeons, blinded to model identity, evaluated each response using a five-point Likert scale across five domains: accuracy, comprehensiveness, readability, relevance, and ethical and safety considerations. The maximum total score per response was 25. Readability was also assessed using the Flesch-Kincaid Grade Level (FKGL) and Flesch Reading Ease Score (FRES). Inter-rater and intra-rater reliability were calculated using intraclass correlation coefficients (ICCs).

resultsThe ChatGPT-4o scored significantly higher in comprehensiveness and clinical detail, whereas DeepSeek R1 produced responses with superior readability, indicated by a lower FKGL (7.5 vs. 10.2) and higher FRES (62.3 vs. 45.6) (p < 0.05). Both models demonstrated high accuracy and safety, with no factual errors identified. Intra-rater reliability was excellent (ICC > 0.81), and inter-rater agreement ranged from fair to substantial (ICC 0.31 to 0.63).

conclusionBoth ChatGPT-4o and DeepSeek R1 are capable of generating accurate, ethically sound, and clinically relevant educational content for patients undergoing TKA. While ChatGPT-4o offers more comprehensive information, DeepSeek R1 provides content that is more accessible to patients with lower health literacy. Model selection should be tailored to the target population to optimize educational effectiveness in clinical practice. The ability of real-time data retrieval to incorporate the most current clinical evidence and guideline updates may further enhance the educational quality, reliability, and clinical relevance of AI-generated patient information.

Indexed as

Arthroplasty, Replacement, KneeComprehensionPatient Education as TopicGenerative Artificial IntelligenceHealth LiteracyHumansLarge Language ModelsReproducibility of Results

Identifiers

PMID41906842
PMCPMC13374050

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.