Evidence map›Paper›PMID 41906755›Full record

ArticleChemistryOpen2026

Site-Specific Surface Modification via Chemoselective Click Reactions on Cyclobutene-Functionalized Monolayers.

Boone W Evans, Kenneth N Hipp, William D Lambert, Wantanee Sittiwong, Rebecca Y Lai, Patrick H Dussault

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ChemistryOpen, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Boone W EvansDepartment of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Kenneth N HippDepartment of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.ORCID https://orcid.org/0000-0001-6529-9996
William D LambertDepartment of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Wantanee SittiwongDepartment of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Rebecca Y LaiDepartment of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.ORCID https://orcid.org/0000-0002-1732-9481
Patrick H DussaultDepartment of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.ORCID https://orcid.org/0000-0002-9834-1350

Funding

National Science Foundation EPS-1004094NCIBC Systems Biology Core NIH NIGMS P20 GM113126NIH HHS RR016544
6 · The paper itself

Abstract

We report the first example of self-assembled monolayers (SAMs) incorporating a cyclobutene-substituted alkanethiol on a gold surface and the efficient modification of these monolayers via inverse electron-demand Diels-Alder (IEDDA) cycloadditions. Mixed SAMs incorporating both cyclobutene- and azide-substituted alkane thiols undergo controlled bisfunctionalization through either sequential or simultaneous performance of IEDDA and copper-assisted alkyne/azide cycloaddition (CuAAC) ligations.

Indexed as

clickcyclobuteneelectrochemical sensinginverse electron‐demand Diels–Alderself‐assembled monolayers

Identifiers

PMID41906755
PMCPMC13140894

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.