ArticleJACC. Advances2026
The HONEST Cohort Study: Rationale and Design of a Nationwide Subcutaneous Implantable Cardioverter-Defibrillator Cohort.
Article in JACC. Advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05302115 (coHOrte fraNcaise Des dEfibrillateurs Sous cuTanés), which is not on this map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
coHOrte fraNcaise Des dEfibrillateurs Sous cuTanés
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The subcutaneous implantable cardioverter-defibrillator (S-ICD) was developed to reduce complications associated with transvenous leads while preserving efficacy in terminating malignant ventricular arrhythmias. However, current evidence supporting the S-ICD is primarily derived from industry-sponsored studies and highly specialized centers. This study aims to offer a comprehensive, nationwide, real-world assessment of all patients who underwent S-ICD implantation in France. The HONEST (coHOrte fraNcaise des dEfibrillateurs Sous cuTanés) cohort is a French nationwide, single-arm, observational ongoing study that enrolled all patients who underwent implantation of an S-ICD (EMBLEM, Boston Scientific) between October 2012 (the first implantation in France) and December 2019. Clinical endpoints are centrally adjudicated. Overall, 4,924 (77% males; 49.9 years) patients, representing 98.2% of all S-ICD implantations during the study period in France, were included. The HONEST study represents the first nationwide cohort evaluating S-ICD recipients to provide contemporary, real-world data. Its goal is to identify areas for improvement and refine strategies to prevent sudden cardiac death. (S-ICD French Cohort Study [HONEST]; NCT05302115).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.