Evidence map›Paper›PMID 41906581›Full record

ArticleJACC. Case reports2026

Multidisciplinary Management Enables Safe Return to Sports in a Pediatric Sudden Cardiac Death Survivor.

Andrea Greco, Estefanía Martinez-Barrios, Oscar Campuzano, José Cruzalegui, Fredy Chipa-Ccasani, Erika Fernanda Merchan-Pinto, Eva Ferrer Vidal-Barraquer, Josep Brugada, Agustin Leonardo Lujan, Georgia Sarquella-Brugada

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrea GrecoArrítmies Pediàtriques, Cardiologia Genètica i Mort Sobtada, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Spain; Arrhythmia, Inherited Cardiac Diseases and Sudden Death Unit, Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain; Faculty of Medicine and Health Sciences, Universitat de Barcelona (UB), Barcelona, Spain.
Estefanía Martinez-BarriosArrítmies Pediàtriques, Cardiologia Genètica i Mort Sobtada, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Spain; Arrhythmia, Inherited Cardiac Diseases and Sudden Death Unit, Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain.
Oscar CampuzanoMedical Science Department, School of Medicine, Universitat de Girona, Girona, Spain; Cardiovascular Genetics Center, University of Girona-IDIBGI, Girona, Spain; Centro de Investigación Biomédica en Red, Enfermedades Cardiovasculares, Madrid, Spain.
José CruzaleguiArrítmies Pediàtriques, Cardiologia Genètica i Mort Sobtada, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Spain; Arrhythmia, Inherited Cardiac Diseases and Sudden Death Unit, Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain; Faculty of Medicine and Health Sciences, Universitat de Barcelona (UB), Barcelona, Spain.
Fredy Chipa-CcasaniArrítmies Pediàtriques, Cardiologia Genètica i Mort Sobtada, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Spain; Arrhythmia, Inherited Cardiac Diseases and Sudden Death Unit, Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain; Faculty of Medicine and Health Sciences, Universitat de Barcelona (UB), Barcelona, Spain.
Erika Fernanda Merchan-PintoArrítmies Pediàtriques, Cardiologia Genètica i Mort Sobtada, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Spain; Arrhythmia, Inherited Cardiac Diseases and Sudden Death Unit, Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain.
Eva Ferrer Vidal-BarraquerSports and Exercise Medicine Unit, Hospital Clinic and Sant Joan de Déu, Barcelona, Spain.
Josep BrugadaCardiology Department, Hospital Clínic, University of Barcelona, Barcelona, Spain.
Agustin Leonardo LujanArrítmies Pediàtriques, Cardiologia Genètica i Mort Sobtada, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Spain; Arrhythmia, Inherited Cardiac Diseases and Sudden Death Unit, Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain; Neuromuscular Disorders Unit, Neurology Department, Sant Joan de Déu Hospital, Esplugues de Llobregat, Spain. Electronic address: agustin.lujan@sjd.es.
Georgia Sarquella-BrugadaArrítmies Pediàtriques, Cardiologia Genètica i Mort Sobtada, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Spain; Arrhythmia, Inherited Cardiac Diseases and Sudden Death Unit, Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain; Medical Science Department, School of Medicine, Universitat de Girona, Girona, Spain; Department of Surgery and Medico-Surgical Specialties, School of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain. Electronic address: georgia.sarquella@sjd.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSudden cardiac death in infants is rare and is often linked to early-onset arrhythmogenic syndromes; unclear causes can lead to overly restrictive behavior owing to fear of recurrence. CASE SUMMARY: We report an 8-month-old male infant who survived a cardiac arrest due to ventricular fibrillation and who was treated with beta-blockers, sympathetic denervation, ablation, loop recorder, and implantable cardioverter-defibrillator. Genetic testing revealed multiple ambiguous variants. Six years of remote monitoring showed no arrhythmia recurrence. Multidisciplinary care enabled gradual, safe reintroduction of moderate physical activity. DISCUSSION: This case underscores the pivotal role of periodic reassessment and personalized management in pediatric cardiac arrest survivors, even in cases where genetic findings are inconclusive.

conclusionsThe identification and treatment of arrhythmic focus, as well as cardiac monitoring, the use of devices for secondary prevention, and shared decision-making support, ensured a safe and selective return to sports. TAKE-HOME MESSAGE: Multidisciplinary care and periodic reassessment support individualized risk stratification and management to facilitate safe sports.

Indexed as

ablationarrhythmogenic syndromesimplantable cardioverter-defibrillatorsportssudden death

Identifiers

PMID41906581
PMCPMC13045568

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.