Evidence map›Paper›PMID 41906572›Full record

ArticleJACC. Case reports2026

Returning to Exercise After Valsalva-Induced Carotid Artery Dissection.

Leah Gutzwiller, Ashley Carlisle, Darian Sharifi, Kevin Tayon, Kristina DeMatas, Sabrina D Phillips, Young Erben, Elizabeth H Dineen, Brian Shapiro, Bryan J Taylor

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Leah GutzwillerDepartment of Cardiovascular Diseases, Mayo Clinic Florida, Jacksonville, Florida, USA. Electronic address: Gutzwiller.leah@mayo.edu.
Ashley CarlisleDepartment of Cardiovascular Diseases, Mayo Clinic Florida, Jacksonville, Florida, USA.
Darian SharifiDepartment of Cardiovascular Diseases, Mayo Clinic Florida, Jacksonville, Florida, USA.
Kevin TayonDepartment of Cardiovascular Diseases, Mayo Clinic Florida, Jacksonville, Florida, USA.
Kristina DeMatasDepartment of Cardiovascular Diseases, Mayo Clinic Florida, Jacksonville, Florida, USA.
Sabrina D PhillipsDepartment of Cardiovascular Diseases, Mayo Clinic Florida, Jacksonville, Florida, USA.
Young ErbenDepartment of Cardiovascular Diseases, Mayo Clinic Florida, Jacksonville, Florida, USA.
Elizabeth H DineenDepartment of Cardiovascular Diseases, Mayo Clinic Florida, Jacksonville, Florida, USA.
Brian ShapiroDepartment of Cardiovascular Diseases, Mayo Clinic Florida, Jacksonville, Florida, USA.
Bryan J TaylorDepartment of Cardiovascular Diseases, Mayo Clinic Florida, Jacksonville, Florida, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough standardized clinical guidelines are lacking, structured exercise training (ExT) can safely improve cardiorespiratory fitness and clinical outcomes after internal carotid artery dissection (ICAD) in persons with vascular Ehlers-Danlos syndrome (vEDS). CASE SUMMARY: We implemented progressive ExT in a 19-year-old man with vEDS after he experienced separate, bilateral ICADs that occurred 12 months apart. The individualized ExT plan included in-clinic and at-home low- to moderate-intensity aerobic and resistance exercise. DISCUSSION: Provider reluctance to prescribe exercise because of tissue fragility and risk of arterial rupture, combined with patient kinesiophobia, often leads people with vEDS to limit physical activity, especially after ICAD. Such patients require education and guidance to safely self-monitor and adhere to ExT. TAKE-HOME MESSAGES: This case demonstrates the feasibility and benefit of structured ExT after ICAD in a person with vEDS. It highlights the need to further develop evidence-based guidelines for ExT in this population.

Indexed as

carotid artery dissectionexercise prescriptionexercise trainingvascular Ehlers-Danlos syndrome

Identifiers

PMID41906572
PMCPMC13045598

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.