ArticleJACC. Case reports2026
Aortic Root Enlargement in a Young Athlete.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAortic enlargement in athletes presents multiple clinical challenges including defining abnormal aortic size, the role of genetic testing, and counseling on sports participation. CASE SUMMARY: A 23-year-old former collegiate volleyball player was incidentally discovered to have an aortic root diameter of 4.4 cm. Genetic testing was negative for any variants associated with heritable thoracic aortic disease (HTAD). Concern remains for HTAD, and corresponding physical activity modifications and a surveillance plan have been established for this athlete. DISCUSSION: Genetic testing for HTAD has limitations as causative mutations are identified in only a minority of suspected cases. While aortic enlargement may be a component of athletic remodeling, reference data in athlete cohorts demonstrate that significant aortic dilation in young athletes is uncommon. TAKE-HOME MESSAGES: Synthesizing reference data from athletic cohorts with established guidelines is essential for navigating the clinical challenge of distinguishing athletic remodeling from aortic pathology in athletes with increased aortic dimensions.
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