Evidence map›Paper›PMID 41906127›Full record

ArticleBMC geriatrics2026

Development and internal validation of a nomogram for identifying intrinsic capacity impairment among community-dwelling older adults in China: a cross-sectional study.

Wenhan Li, Aihong Liu, Kemeng Zhang, Yi Zhang, Sui Huang, Mengchen Liu, Bijin Luo, Yuxia Shi, Jing Ge, Ping He

Abstract readValidation Study
In one paragraph

Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Wenhan Li *Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Aihong Liu *Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Kemeng ZhangDepartment of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Yi ZhangDepartment of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Sui HuangDepartment of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Mengchen LiuDepartment of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Bijin LuoDepartment of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Yuxia ShiDepartment of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Jing GeDepartment of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. 11006831@qq.com.
Ping HeDepartment of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. pinghe@hust.edu.cn.

Funding

Health Commission of Hubei Province No. 08.01.23004
6 · The paper itself

Abstract

backgroundIntrinsic capacity (IC), reflecting an individual’s composite physical and mental capacities, is a key indicator of healthy ageing. Early identification of IC impairment among community-dwelling older adults may help support timely assessment and management in community settings. This study aimed to develop and internally validate a nomogram for identifying IC impairment among community-dwelling older adults.

methodsThis cross-sectional study included community-dwelling adults aged ≥ 60 years. IC impairment was operationally defined as impairment in at least one domain of the World Health Organization Integrated Care for Older People (WHO-ICOPE) framework. Candidate variables included demographic characteristics, lifestyle factors, fall history, chronic disease burden, medication use, handgrip strength, and appendicular skeletal muscle mass index (ASMI). Least absolute shrinkage and selection operator (LASSO) regression with 10-fold cross-validation was used for variable selection, and retained variables were entered into a multivariable logistic regression model to construct a nomogram. Model performance was evaluated using the area under the receiver operating characteristic curve (AUC), calibration, Brier score, and decision curve analysis (DCA).

resultsThe prevalence of IC impairment was 72.7%. At the more parsimonious λ.1se, age, history of falls, and appendicular skeletal muscle mass index (ASMI) were retained and used to develop the final model. The nomogram showed good discrimination, with AUCs of 0.8209 (95% CI: 0.7916–0.8502) in the training set and 0.7902 (95% CI: 0.7430–0.8373) in the validation set. Calibration was acceptable, and DCA suggested potential net benefit across a relatively wide range of threshold probabilities.

conclusionsA nomogram incorporating age, history of falls, and ASMI was developed and internally validated for identifying IC impairment among community-dwelling older adults. This model may serve as a useful reference for early community screening and stratified assessment. Further external validation is needed.

Indexed as

Geriatric AssessmentIndependent LivingNomogramsAgedAged, 80 and overAging in PlaceChinaCross-Sectional StudiesFemaleHand StrengthHumansMaleMiddle AgedCommunity-dwelling older adultsIntrinsic capacityNomogramWHO-ICOPE

Identifiers

PMID41906127
PMCPMC13185353

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