Evidence map›Paper›PMID 41906123›Full record

ArticleBMC public health2026

Epidemiological characteristics and spatiotemporal trend analysis of human brucellosis in Shanxi Province, China, 2014-2024.

Yongfei Bai, Pei Lei, Zhaoyu Fan, Yuzan Bai, Kaiguang Zhang, Fengping Wang, Xue Dong, Ruiqi Gao, Wenqing Wang, Xi Zhang and 1 more

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Article in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Yongfei Bai *Shanxi Provincial Center for Disease Control and Prevention, Taiyuan, 030012, China.
Pei Lei *School of Public Health, Changzhi Medical College, Changzhi, 046000, China.
Zhaoyu FanSchool of Nursing, Changzhi Medical College, Changzhi, 046000, China.
Yuzan BaiSchool of Basic Medical Sciences, Changzhi Medical College, Changzhi, 046000, China.
Kaiguang ZhangSchool of Public Health, Changzhi Medical College, Changzhi, 046000, China.
Fengping WangSchool of Public Health, Changzhi Medical College, Changzhi, 046000, China.
Xue DongSchool of Public Health, Changzhi Medical College, Changzhi, 046000, China.
Ruiqi GaoSchool of Public Health, Changzhi Medical College, Changzhi, 046000, China.
Wenqing WangNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, China. wang_wenging1225@163.com.
Xi ZhangClinical Research & Innovation Unit, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. zhangxi@xinhuamed.com.cn.
Huaxiang RaoSchool of Public Health, Changzhi Medical College, Changzhi, 046000, China. raohuaxiang2006006@163.com.

Funding

Doctor research startup foundation of Changzhi Medical College No. BS201921Undergraduate Innovation and Entrepreneurship Training Program 20251081
6 · The paper itself

Abstract

backgroundBrucellosis poses a significant public health challenge. This study aimed to analyze the epidemiological characteristics and spatiotemporal evolution of human brucellosis in Shanxi Province to inform targeted prevention strategies.

methodsWe obtained monthly and county-level human brucellosis case counts and incidence rates for Shanxi Province from 2014 to 2024 using China’s Disease Prevention and Control Information System. Joinpoint software was used to identify the temporal trends. ArcGIS was used for global Moran’s I to assess overall clustering, followed by Local Moran’s I to identify high-high and low-low clusters, and Getis-Ord Gi* to detect hot and cold spots, and standard deviation ellipses to assess directional diffusion. The SaTScan was used to identify high-risk clusters.

resultsA total of 51,789 cases were reported, the age-standardized annual incidence rate was 10.4 per 100,000 (95% confidence interval [CI]: 8.4 per 100,000, 12.4 per 100,000) and the average annual percent change was − 5.00% (95% CI: -8.78%, -0.25%). A turning point in the incidence of the diseasewas observed in 2017, with peak incidence in May. Spatial analysis revealed significant clustering (Global Moran’s I: 0.307–0.498, all P < 0.001) and the center shifting southwestward. Spatiotemporal scanning revealed the most likely clusters in northern Shanxi (LLR2014-2015 = 3531.07, LLR2019-2021 = 5111.36, RR2014-2015 = 4.32, RR2019-2021 = 4.89, P < 0.001).

conclusionsHuman brucellosis in Shanxi has increased since 2017, with spatial diffusion from north to south and distinct seasonality. Enhanced surveillance and targeted interventions for high-risk populations and emerging disease hotspots are thus urgently required.

Indexed as

BrucellosisAdolescentAdultChildChinaCluster AnalysisFemaleHumansIncidenceMaleMiddle AgedSpatio-Temporal AnalysisEpidemiological characteristicsHuman brucellosisSpatial autocorrelationSpatiotemporal scanningStandard deviation ellipse

Identifiers

PMID41906123
PMCPMC13151133

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.