Evidence map›Paper›PMID 41906092›Full record

ArticleBMC cardiovascular disorders2026

Incidence of hypertension and factors associated with blood pressure control among older adults living with HIV in Western Kenya: a retrospective cohort study.

Jepchirchir Kiplagat, Richard Mugo, Beverly Musick, Ann Mwangi, Constantin T Yiannoutsos, Kara Wools-Kaloustian

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Article in BMC cardiovascular disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jepchirchir KiplagatAcademic Model Providing Access to Healthcare, Eldoret, Kenya. chiri2809@gmail.com.
Richard MugoAcademic Model Providing Access to Healthcare, Eldoret, Kenya.
Beverly MusickSchool of Medicine, Department of Biostatistics and Health Data Science, Indiana University, Indianapolis, USA.
Ann MwangiAcademic Model Providing Access to Healthcare, Eldoret, Kenya.
Constantin T YiannoutsosAcademic Model Providing Access to Healthcare, Eldoret, Kenya.
Kara Wools-KaloustianAcademic Model Providing Access to Healthcare, Eldoret, Kenya.

Funding

East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional ConsortiumU01AI069911 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI Leslie Anne Enane, AGGREY SEMWENDERO SEMEERE · 2006 to 2026
$57.7M
NPGH LEADERs YR12: OBSSR (Greenberg, Ngwafong Mukere) & NIBIB (Lee)D43TW009345 · FIC · UNIVERSITY OF WASHINGTON · PI Dibyadyuti Datta, Chandy C. John · 2017 to 2026
$15.2M
FIC NIH HHS D43TW009345NIAID NIH HHS U01 AI069911
6 · The paper itself

Abstract

backgroundPeople living with HIV are living longer due to expanded access to antiretroviral treatment (ART). As they age, their risk of hypertension is greater due to HIV-immune activation and long-term use of some antiretrovirals. Screening and treatment of hypertension and monitoring hypertension control are key strategies for averting morbidity and mortality from cardiovascular disease and improving the health outcomes of older adults living with HIV (OALWH). We sought to estimate the incidence of hypertension and determine the proportion of blood pressure control among OALWH in western Kenya.

methodsWe analyzed deidentified clinical data for OALWH (≥ 50 years) attending a large HIV care and treatment program in western Kenya, between January 1, 2016, and August 24, 2021. Hypertension was defined by two consecutive blood pressure (BP) readings with systolic BP (SBP) ≥ 140 and diastolic BP (DBP) ≥ 90, a clinical diagnosis of hypertension, or the use of hypertension medication. Screening and monitoring were defined as having BP measurements in individuals without or with hypertension, respectively. Descriptive statistics and logistic regression assessed baseline characteristics and factors associated with hypertension. Linear mixed models estimated the rates of screening, monitoring, BP control, and sex differences.

resultsOf 6216 eligible OALWH, 52.5% were female and 23.0% were hypertensive at baseline. Baseline factors associated with hypertension included, age, body mass index, sex, prior ART exposure and having health insurance. On follow up, 91.1% (95% CI, 90.8%-91.4%) of non-hypertensive individuals were screened. The incidence of hypertension was 84 cases per 1000-person years. Of individuals with hypertension, 91.2% (95% CI, 90.9%-91.5%) were monitored and 47.9% (95% CI, 46.6%, 49.1%) achieved BP control. No gender differences were identified in BP screening, monitoring, or control rates.

conclusionThe high incidence of hypertension with less than half of those with hypertension achieving controlled BP, reveals a significant gap between detection and effective management. This highlights the needs not only in the continuity of hypertension screening but also the need for strengthened hypertension management within HIV programs.

Indexed as

Antihypertensive AgentsBlood PressureHIV InfectionsHIV Long-Term SurvivorsHypertensionAgedAge FactorsAnti-HIV AgentsFemaleHumansIncidenceKenyaMaleMiddle AgedRetrospective StudiesRisk AssessmentAnti-HIV AgentsAntihypertensive AgentsHIVHypertensionIntegrationOlder adultsUnmet needs

Identifiers

PMID41906092
PMCPMC13154848

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.