Evidence map›Paper›PMID 41905955›Full record

ArticleVox sanguinis2026

Effects of the start date of refrigeration on functions of delayed cold-stored platelets.

Hisae Fuse, Shinobu Wakamoto, Fuminori Arisawa, Takumi Kanashiki, Mitsuhiro Fujihara, Mitsuaki Akino, Yoshihiro Torimoto

Abstract read
In one paragraph

Article in Vox sanguinis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hisae FuseJapanese Red Cross Hokkaido Block Blood Center, Sapporo, Japan.
Shinobu WakamotoJapanese Red Cross Hokkaido Block Blood Center, Sapporo, Japan.
Fuminori ArisawaJapanese Red Cross Hokkaido Block Blood Center, Sapporo, Japan.
Takumi KanashikiJapanese Red Cross Hokkaido Block Blood Center, Sapporo, Japan.
Mitsuhiro FujiharaJapanese Red Cross Hokkaido Block Blood Center, Sapporo, Japan.
Mitsuaki AkinoJapanese Red Cross Hokkaido Block Blood Center, Sapporo, Japan.
Yoshihiro TorimotoJapanese Red Cross Hokkaido Block Blood Center, Sapporo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe functions of cold-stored platelets (PLTs) have recently been re-evaluated. In Japan, cold storage may be started immediately after blood collection (Day 0, control group), after the period for improving bacterial screening sensitivity has ended (Day 2, DCS2) and after the expiration date of room-temperature storage has ended (Day 5, DCS5). The present study investigated the effects of different cold storage start dates on PLT function. MATERIALS AND

methodsConcentrated PLTs, collected using an apheresis device, were placed in an additive solution (Terumo-platelet additive solution+, Terumo BCT) and then divided into three groups with different cold storage start dates (days 0, 2 or 5). The three groups were stored until Day 21, and various PLT function parameters-including aggregation (adenosine diphosphate [ADP] + collagen-induced and ristocetin-induced aggregation), viscoelasticity (maximum clot firmness [MCF], clotting time and α-angle) and PLT activation (CD62P, PAC-1, CD63 and Annexin V)-were measured and compared.

resultsComparisons of results until Day 14 revealed that among the PLT function parameters examined, only ADP + collagen-induced aggregation and MCF showed a deterioration in DCS2 and DCS5. However, aggregation and MCF values in DCS2 and DCS5 on Day 10 were not markedly different from those in the control group on Day 14 (US expiration date).

conclusionPLTs stored at room temperature for 2 or 5 days after collection and then refrigerated may be preserved until Day 10.

Indexed as

Blood PlateletsBlood PreservationCryopreservationRefrigerationCold TemperatureHumansPlatelet ActivationPlatelet AggregationTime Factorsadditive solutioncold‐stored plateletdelayed cold‐stored plateletT‐PAS+

Identifiers

PMID41905955
PMCPMC13356993

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.