Evidence map›Paper›PMID 41905607›Full record

ArticleAmerican journal of preventive medicine2026

Nonmonotonic Associations Between Cannabis Use Frequency and Alcohol Use in a Statewide Sample of Young Adults From Washington State.

Charles B Fleming, Brian H Calhoun, Isaac C Rhew, Jason R Kilmer, Mary E Larimer, Katarina Guttmannova

Abstract read
In one paragraph

Article in American journal of preventive medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Charles B FlemingDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington. Electronic address: cnbflem@uw.edu.
Brian H CalhounDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington.
Isaac C RhewDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington.
Jason R KilmerDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington; Department of Psychology, University of Washington, Seattle, Washington.
Mary E LarimerDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington; Department of Psychology, University of Washington, Seattle, Washington.
Katarina GuttmannovaDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington.

Funding

Scientific/Technical CoreP2CHD042828 · NICHD · UNIVERSITY OF WASHINGTON · PI SARA R. CURRAN · 2017 to 2026
$6.3M
Covid-19 pandemic and changes in the prevalence, patterns, and trajectories of substance use and related health risk outcomes among young adults in WA State: Administrative supplement.R01DA057705 · NIDA · UNIVERSITY OF WASHINGTON · PI GUTTMANNOVA, KATARINA · 2022 to 2024
$1.3M
NICHD NIH HHS P2C HD042828NIDA NIH HHS R01 DA057705
6 · The paper itself

Abstract

introductionYoung adult cannabis use is positively associated with alcohol use, but some research suggests that individuals who use cannabis daily or near daily drink less than individuals who use cannabis less frequently. This study delineated nonmonotonic associations between cannabis use frequency and alcohol use among young adults in Washington state.

methodsData were from young adults recruited into the Washington Young Adult Health Study between 2015 and 2022 (N=15,217; aged 18-25 years at recruitment). After baseline, participants completed annual follow-up surveys, providing 43,423 observations covering ages 18-33 years. In multilevel models, past-month any heavy episodic drinking and days of alcohol use were regressed on concurrent past-month cannabis use days, which was indicator coded into 8 categories ranging from no use to daily use. Data were analyzed in the summer of 2025.

resultsBoth heavy episodic drinking prevalence and alcohol use days were lowest when no cannabis use was reported and were positively associated with cannabis use across cannabis use frequency between none and 5-9 days. Both measures of alcohol use were lower at upper frequencies of cannabis use such that daily or near daily cannabis use (≥25 days) was associated with less drinking than occasional cannabis use (5-24 days). Nonmonotonic associations were present across age groups (18-20, 21-25, ≥26 years).

conclusionsNonmonotonic associations between cannabis and alcohol use may be consistent with substance use specialization among some young adults who use cannabis or alcohol frequently.

Indexed as

Alcohol DrinkingMarijuana SmokingMarijuana UseAdolescentAdultFemaleHumansMalePrevalenceWashingtonYoung Adult

Identifiers

PMID41905607
PMCPMC13158934

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.