Evidence map›Paper›PMID 41904759›Full record

ArticleMikrochimica acta2026

A quinolinium-based fluorescent probe with high quantum yield for bisulfite detection and its applications in food testing, solid-phase immobilization, smartphone-assisted portable detection, and cell imaging.

Ruiqi Ren, Long Wang, Ziqi Ma, Mingyu Tian, Tianyu Liang, Chengyan Wu, Lijun Tang, Yang Li, Keli Zhong, Xiaomei Yan

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Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Ruiqi RenCollege of Chemistry, Bohai University, Jinzhou, 121013, China.
Long WangCollege of Chemistry, Bohai University, Jinzhou, 121013, China.
Ziqi MaCollege of Laboratory Medicine, Dalian Medical University, Dalian, 116044, China.
Mingyu TianCollege of Chemistry, Bohai University, Jinzhou, 121013, China.
Tianyu LiangCollege of Chemistry, Bohai University, Jinzhou, 121013, China.
Chengyan WuCollege of Chemistry, Bohai University, Jinzhou, 121013, China.
Lijun TangCollege of Chemistry, Bohai University, Jinzhou, 121013, China. ljtang@bhu.edu.cn.
Yang LiCollege of Chemistry, Bohai University, Jinzhou, 121013, China.
Keli ZhongCollege of Chemistry, Bohai University, Jinzhou, 121013, China.
Xiaomei YanCollege of Laboratory Medicine, Dalian Medical University, Dalian, 116044, China. xmyan1978@sina.com.

Funding

General project of Liaoning Provincial Department of Education LJ212410167066, JTTMS1618National Natural Science Foundation of China 22278038Open Project of the Institute of Ocean of Bohai University BDHYYJY2024010
6 · The paper itself

Abstract

To achieve rapid and accurate detection of bisulfite (HSO3−), we developed two novel fluorescent probes, PTQ and PSQ, featuring large Stokes shifts, a broad detection range, and high fluorescence quantum yields, based on intramolecular charge transfer mechanism. Among them, PTQ exhibits superior selectivity and sensitivity, accompanied by a distinct color change and a strong turn-on fluorescence response upon recognition of HSO3−. Leveraging these properties, PTQ enables the effective detection of HSO3− in food samples. Furthermore, we constructed test strips, agarose gels, and a smartphone-assisted detection platform for the on-site monitoring of SO2 gas and HSO3− in aqueous solutions, and preliminarily explored the potential application of PTQ as an anti-counterfeiting ink. Notably, PTQ also possesses mitochondria-targeting ability, enabling the visualization and imaging of exogenous and endogenous bisulfite in live cells and zebrafish. This work highlights the versatile potential of PTQ in environmental monitoring, food safety inspection, and bioimaging, providing a powerful tool for detecting SO2 derivatives from abiotic samples to living organisms.

Indexed as

Fluorescent DyesFood AnalysisSmartphoneSulfitesAnimalsFluorescent Chemosensor CompoundsHeLa CellsHumansLimit of DetectionOptical ImagingSpectrometry, FluorescenceZebrafishFluorescent Chemosensor CompoundsFluorescent Dyeshydrogen sulfiteSulfitesBioimagingBisulfiteFluorescent probeFood detectionQuinolinium

Identifiers

PMID41904759

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.