ArticleThe American journal on addictions2026
Brief Report: Opioid-related disorders increase patient-directed discharge in admissions for hemorrhagic or ischemic stroke.
Article in The American journal on addictions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
BACKGROUND AND
objectivesOpioid use has been linked to increased stroke incidence and severity; however, data on effects during acute stroke hospitalization are limited.
methodsWe used the 2016-2020 National Inpatient Sample to evaluate the effects of opioid disorders on patient-directed discharge (PDD) and length of stay (LOS) in 3,101,545 patients.
resultsOn multivariate analysis, opioid disorders were independently associated with discharge AMA (aOR: 2.29; 95% CI: 1.98-2.65) and longer LOS (β: 1.5, SE: 0.138; p < .001). DISCUSSION AND
conclusionsOpioid disorders may predispose PDD and prolonged hospital courses in stroke admissions. SCIENTIFIC SIGNIFICANCE: Opioid disorders may warrant targeted inpatient management and health system planning in stroke.
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