Evidence map›Paper›PMID 41904414›Full record

Observational studyBMC cardiovascular disorders2026

Association between blood urea nitrogen-to-albumin ratio and postoperative acute kidney injury in patients undergoing off-pump coronary artery bypass grafting: a retrospective observational study.

Fangyi Luo, Yuxi Hou, Shuwen Li, Sheng Wang

Abstract readObservational Study
In one paragraph

Observational study in BMC cardiovascular disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Fangyi Luo *Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Yuxi Hou *Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Shuwen LiDepartment of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Sheng WangDepartment of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China. shengwang@mail.ccmu.edu.cn.

Funding

Noncommunicable Chronic Diseases-National Science and Technology Major Project No. 2023ZD0504404
6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) is a common complication after off-pump coronary artery bypass grafting (OPCABG). Although the blood urea nitrogen-to-albumin ratio (BAR) has shown prognostic value in other settings, its association with postoperative AKI in OPCABG remains unclear.

methodsMultivariable logistic regression was used to evaluate the association between BAR and postoperative AKI. Predictive performance was assessed using receiver operating characteristic (ROC) analysis and calibration, with internal validation by bootstrap resampling. Incremental value was evaluated using net reclassification improvement (NRI), integrated discrimination improvement (IDI) and decision curve analysis (DCA). Inverse probability of treatment weighting (IPTW) and sensitivity analyses were conducted to examine robustness.

resultsBAR was independently associated with postoperative AKI, both as a continuous variable (per 1-standard deviation [SD] increase: odds ratio [OR] 1.90, 95% confidence interval [CI] 1.58–2.27) and as a categorical variable (BAR≥ 0.2 mmol/g: OR 4.56, 95% CI 2.99–6.94). This association remained robust in IPTW and sensitivity analyses. Adding BAR improved discrimination (AUC: 0.754 vs. 0.694; ΔAUC = 0.060, p < 0.001) with stable performance after bootstrap validation. Reclassification and DCA further supported its potential value for early AKI risk stratification.

conclusionsElevated preoperative BAR was independently associated with an increased risk of postoperative AKI and may serve as a useful risk marker in patients undergoing OPCABG.

Indexed as

Acute Kidney InjuryBlood Urea NitrogenCoronary Artery Bypass, Off-PumpSerum AlbuminSerum Albumin, HumanAgedBiomarkersFemaleHumansMaleMiddle AgedOdds RatioPredictive Value of TestsRetrospective StudiesRisk AssessmentRisk FactorsALB protein, humanBiomarkersSerum AlbuminSerum Albumin, HumanAcute kidney injuryAlbuminBlood urea nitrogenCoronary artery bypass graftingRisk stratification

Identifiers

PMID41904414
PMCPMC13151166

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.