ArticleSpine deformity2026
Complications and outcomes of spinal deformity correction in patient with open neural tube defects.
Article in Spine deformity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo evaluate surgical complications, functional and neurological outcomes of spinal deformity correction in children who underwent open neural tube defects (ONTDs) repair earlier.
methodsWe analyzed 65 patients with treated ONTDs (myelomeningocele and myeloschisis) who underwent spinal deformity correction at a single center from 2010 to 2023. Statistical methods included logistic regression to assess predictors of early and late complications.
resultsHigher level of spinal cord malformation and spina bifida associated with higher rate of non-ambulatory status, C-shaped thoracolumbar scoliosis, lumbar kyphosis rate, and severity. Early complications occurred in 37% and included wound problems (31%), pneumothorax (6%), and screw malposition (5%). Late complications were noted in 39%, including late-onset implant exposure through skin (32%), rod fracture (14%), and screw loosening (10%). Intraoperative blood loss correlated with early wound complications (p = 0.004, OR 1.01, 95% CI 1.01-1.02) and pelvic fixation correlated with pseudoarthrosis (p = 0.027, OR 7.13, 95% CI 1.25-40.79). Neurological function remained stable during follow-up, whereas functional independence improved, but much less than in healthy individuals.
conclusionsLevel of spinal cord malformation in ONTDs correlated with walking status and deformity type and severity. Spinal deformity correction after ONTDs repair carries a high complication rate. Surgical intervention likely does not affect neurological and functional status significantly, but functional independence gradually improves.
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