Evidence map›Paper›PMID 41904271›Full record

ArticleScientific reports2026

Multiple introgression events from ghost Rüppell's fox mitochondrial lineages into red fox.

Rita Gomes Rocha, Ali Adan Hassan, Sadık Demirtaş, Mariana Meneses-Ribeiro, Joana L Rocha, İslam Gündüz, Raquel Godinho

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Rita Gomes RochaInBIO Laboratório Associado, CIBIO-Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, Vairão, Portugal. rgrocha@cibio.up.pt.
Ali Adan HassanDepartment of Biology, Faculty of Sciences, Ondokuz Mayis University, Samsun, Türkiye.
Sadık DemirtaşDepartment of Molecular Biology and Genetics, Faculty of Sciences, Ondokuz Mayıs University, Samsun, Türkiye.
Mariana Meneses-RibeiroInBIO Laboratório Associado, CIBIO-Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, Vairão, Portugal.
Joana L RochaDepartment of Biology, New York University, New York, USA.
İslam GündüzDepartment of Biology, Faculty of Sciences, Ondokuz Mayis University, Samsun, Türkiye.
Raquel GodinhoInBIO Laboratório Associado, CIBIO-Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, Vairão, Portugal. rgodinho@cibio.up.pt.

Funding

Fundação para a Ciência e a Tecnologia 10.54499/2022.00505.CEECIND/CP1730/CT0002Fundação para a Ciência e a Tecnologia 10.54499/2022.07926.CEECIND/CP1730/CT0008Scientific Research Coordination Unit of Ondokuz Mayıs University PYO.FEN.1904.19.005
6 · The paper itself

Abstract

Mitochondrial introgression has been reported between red fox (Vulpes vulpes) and Rüppell’s fox (Vulpes rueppellii). While an evolutionary scenario of old divergence followed by recent mitochondrial introgression has been proposed, the directionality, prevalence, and timing of this event remain unclear. To further investigate this scenario, we analysed mitogenomes (n=85), including four newly generated red fox mitogenomes from Türkiye and a new Rüppell’s fox mitogenome from the United Arab Emirates, and partial mitochondrial DNA sequences (n=320) from both species across their ranges, including a newly comprehensive sampling in the Anatolian Peninsula (n=80). Our results are consistent with unidirectional mitochondrial introgression from the desert-adapted Rüppell’s fox into the generalist red fox, likely driven by climatic shifts promoting secondary contact and asymmetrical reproductive behaviour. Phylogenetic analysis unveiled two deeply divergent mitochondrial lineages of Rüppell’s fox sampled among red fox individuals: one distributed across Türkiye, Iran and Tunisia, and another restricted to Iran, suggesting that likely now-extinct (ghost) mitochondrial lineages may have introgressed into red foxes at least twice. Estimates of the time to the most recent common ancestor indicate that introgressed and contemporary Rüppell’s fox mitochondrial lineages diverged approximately 230 kya, predating the current intraspecific mitochondrial diversification of Rüppell’s fox lineages (~72 kya). This study highlights how comprehensive mitogenomic data and exhaustive regional surveys are critical for elucidating the complexity of introgression patterns in closely related canids.

Indexed as

DNA, MitochondrialFoxesGenetic IntrogressionGenome, MitochondrialAnimalsEvolution, MolecularPhylogenyDNA, MitochondrialAnatolian PeninsulaCanidaeGhost introgressionMitogenomesPhylogeny

Identifiers

PMID41904271
PMCPMC13040000

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