ArticleNature communications2026
Exploring how deep learning decodes anomalous diffusion via Grad-CAM.
Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
3 authors.
Funding
Abstract
While deep learning has been successfully applied to the data-driven classification of anomalous diffusion mechanisms, how the algorithm achieves the feat remains a mystery. Using a well-known technique aimed at achieving explainable AI, namely the Gradient-weighted Class Activation Map (Grad-CAM), we investigate how deep learning (implemented by ResNets) recognizes the distinctive features of a particular anomalous diffusion model from the raw trajectory data. Our results show that Grad-CAM reveals the portions of the trajectory that hold crucial information about the underlying mechanism of anomalous diffusion, which can be utilized to enhance the robustness of the trained classifier against the measurement noise. Moreover, we observe that deep learning distills unique statistical characteristics of different diffusion mechanisms at various spatiotemporal scales, with larger-scale (smaller-scale) features identified at higher (lower) layers.
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Registered trials
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