Evidence map›Paper›PMID 41904093›Full record

ArticleAcademic radiology2026

Patients' and Providers' Perspective of a Multi-level Approach to Improve Participation in Low-dose CT for Lung Cancer Screening (Empower LCS): A Mixed-Methods Analysis.

Maedeh Sharifian, Michael A Hoyt, Aarushi Madan, Sunmin Lee, Tan Q Nguyen, Gelareh Sadigh

Registry-linked trialAbstract read
In one paragraph

Article in Academic radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06000683 (Empowering Patients' Lung Cancer Screening Uptake), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06000683 nacompletednot on this map

Empowering Patients' Lung Cancer Screening Uptake (Empower LCS)

TypeinterventionalSponsorUniversity of California, IrvineRan2023 to 2025Enrolled79ConditionsLung CancerArmsPatient education, Referral to financial navigation resources, Patient Reminders, Provider Reminers
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maedeh SharifianDepartment of Radiological Sciences, University of California, Irvine, CA (M.S., A.M., G.S.).
Michael A HoytDepartment of Population Health and Disease Prevention, University of California Irvine, Irvine, CA (M.A.H.).
Aarushi MadanDepartment of Radiological Sciences, University of California, Irvine, CA (M.S., A.M., G.S.).
Sunmin LeeDepartment of Medicine, University of California Irvine, Irvine, CA (S.L.).
Tan Q NguyenDepartment of Family Medicine, University of California Irvine, Irvine, CA (T.Q.N.).
Gelareh SadighDepartment of Radiological Sciences, University of California, Irvine, CA (M.S., A.M., G.S.). Electronic address: gsadigh@uci.edu.

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
NCI NIH HHS P30 CA062203
6 · The paper itself

Abstract

RATIONALE AND

objectivesLung cancer screening (LCS) utilization remains suboptimal. We examined the experience of patients and primary care providers (PCPs) participating in a multilevel intervention addressing LCS barriers.

methodsEmpower LCS is a single-arm pilot feasibility trial evaluating feasibility, acceptability and potential impact of a multilevel intervention, including a decision aid, patient reminders, PCP electronic medical record (EMR) notifications, and support for health-related social needs (HRSNs) for patients screening positive for HRSNs, to improve LCS completion. Using a mixed-methods design, quantitative surveys assessed the helpfulness of intervention components. Additionally, 11 patients and five PCPs participated in 30-minute semi-structured interviews, analyzed through a theoretically driven thematic approach.

resultsOf 70 participants, 41 completed experience questions at 6-months (mean age 61.7 ± 6.4; 63.4% male). Most patients found the intervention helpful: 61.5% (24/39) decision aid, 67.5% (27/40) patient reminder, and 70.7% (29/41) PCP's EMR notification. Most patients viewed LCS as important and wanted to discuss it with their provider. However, some patients felt providers were hesitant to engage fully or lacked knowledge about LCS eligibility. Patient-reported barriers included scheduling challenges, insurance delays, and smoking-related stigma. Many said Empower LCS increased awareness and motivation. Providers reported routinely discussing smoking history and identified low patient awareness, insurance issues, competing priorities, and patient radiation concerns as barriers. They found the intervention appropriate for primary care, especially with better patient education and EMR notifications.

conclusionBoth patients and providers were receptive to LCS and thought the Empower LCS intervention had the potential to increase LCS in routine practice.

trial registrationThis study is registered at www. CLINICALTRIALS: gov: NCT06000683.

Indexed as

Attitude of Health PersonnelEarly Detection of CancerLung NeoplasmsPatient ParticipationTomography, X-Ray ComputedAdherence InterventionsAgedElectronic Health RecordsFeasibility StudiesFemaleHumansMaleMiddle AgedPilot ProjectsRadiation DosageReminder SystemsLung cancer screeningMulti-level interventionPatientsProvidersQualitative interviews

Identifiers

PMID41904093
PMCPMC13077605

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.