ArticleClinical medicine (London, England)2026
Post-surgical electron beam radiotherapy for prevention of keloid recurrence: A retrospective study of 619 cases demonstrating low recurrence (6.5%) with optimised 18 Gy in two fractions.
Article in Clinical medicine (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Hypertension: A common, yet poorly managed condition. What can we do better?Clinical medicine (London, England) · 2026Article
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10 authors.
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Abstract
backgroundAlthough post-surgical radiotherapy is common in keloid management, factors influencing its efficacy remain unclear. The aim of this study is to investigate postoperative electron beam radiotherapy's impact on recurrence and adverse effects.
methodsA retrospective study was conducted to evaluate the recurrence rates and complications across three radiation schemes: 17.5 Gy / five fractions, 20 Gy / four fractions, and 18 Gy / two fractions.
resultsThe overall recurrence rate was 6.5%, with the lowest recurrence (2.8%) observed in the 18 Gy / two-fraction regimen. Radiation schemes, lesion condition (type, location, and duration), and family history were associated with post-surgical recurrence. Furthermore, hyperpigmentation (32%) and dermatitis (11.8%) were identified as significant adverse events. No radiation-related cancers were observed during follow-up.
conclusionThe 18 Gy / two-fraction regimen post-surgical electron beam radiotherapy emerged as the most effective and safe option for keloid recurrence prevention. Features, including lesion type, location, family history and disease duration should be combined to guide therapeutic strategy.
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