In Situ Characterization Reveals an Impaired Fibril Response to Loading Following Unloading during Early Achilles Tendon Healing.

Isabella Silva Barreto, Kunal Sharma, Maria Pierantoni, Md Abdul Alim, Ana Diaz, Pernilla Eliasson, Hanna Isaksson

Abstract read

In one paragraph

Article in ACS biomaterials science & engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Isabella Silva BarretoDepartment of Biomedical Engineering, Lund University, SE-223 63 Lund, Sweden.ORCID 0000-0002-9413-8320

Kunal SharmaDepartment of Biomedical Engineering, Lund University, SE-223 63 Lund, Sweden.ORCID 0000-0003-3063-3709

Maria PierantoniDepartment of Biomedical Engineering, Lund University, SE-223 63 Lund, Sweden.

Md Abdul AlimDepartment of Biomedical and Clinical Sciences, Linköping University, SE-581 83 Linköping, Sweden.

Ana DiazPSI Center for Photon Science, Paul Scherrer Institute, CH-5232 Villigen PSI, Switzerland.ORCID 0000-0003-0479-4752

Pernilla EliassonDepartment of Biomedical and Clinical Sciences, Linköping University, SE-581 83 Linköping, Sweden.

Hanna IsakssonDepartment of Biomedical Engineering, Lund University, SE-223 63 Lund, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Achilles tendon is the most frequently injured tendon in humans. Despite extensive research to understand its healing, there are still no clear rehabilitation guidelines to ensure full recovery and prevent reruptures. This could partly be due to limited understanding of how loading during tendon healing affects the multiscale mechanical response and in particular the nanoscale. We combined synchrotron small-angle X-ray scattering mapping with

Indexed as

Achilles TendonTendon InjuriesWound HealingAnimalsBiomechanical PhenomenaCollagenMaleRatsScattering, Small AngleStress, MechanicalTensile StrengthWeight-BearingCollagencollagenmechanicsnanoscalesmall-angle X-ray scattering

Identifiers

PMID41903210

DOI10.1021/acsbiomaterials.5c01976

PMCPMC13080769

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.