Evidence map›Paper›PMID 41903027›Full record

ArticleBiogerontology2026

Lifespan stops at death, but when does healthspan stop?

Suresh I S Rattan

Abstract readEditorial
PubMed Publisher
In one paragraph

Article in Biogerontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Diets Rich inNutrients · 2026
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Suresh I S RattanDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark. rattan@mbg.au.dk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This editorial delineates the conceptual distinctions among lifespan, longevity, and healthspan in biogerontology. Lifespan is defined as the chronological duration from birth to biological death. Longevity refers to the capacity for survival beyond the species-typical average and is best understood probabilistically rather than as a predetermined limit. Healthspan, by contrast, lacks a uniform definition but is most commonly described as the period of life free from major chronic disease and significant functional decline. Healthspan is often considered to end with the onset of clinically significant impairment(s) that compromise physical or mental independence, irrespective of chronological age. Yet survival often persists beyond this point, highlighting the roles of medical, physiological, technological, and psychosocial compensations that enable continued existence despite markedly reduced health. Therefore, framing health through the lens of homeodynamic space positions it as the ability to sustain physical and mental independence adequately. Greater conceptual clarity is essential to enhance research alignment, improve cross-study comparability, and guide interventions that extend not merely chronological lifespan, but meaningful, context-sensitive healthy lifespan, even in the presence of disease(s). Biogerontology invites original research, review, and perspective articles addressing these issues.

Indexed as

AgingLongevityAnimalsHumansLife ExpectancyAge-related diseasesHomeodynamicsHomeostasisHormesisMortalitySociety

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.