ArticleVeterinary research communications2026
Antimicrobial resistance analysis of Escherichia coli isolated from foxes in China.
Article in Veterinary research communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Genomic analysis of virulence and antimicrobial resistance in Klebsiella isolates from farmed sika deer.BMC genomics · 2026Article
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Authors and funding
18 authors.
Funding
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Abstract
Escherichia coli (E. coli) is a common gut commensal and an important opportunistic pathogen in humans and animals. Here, we investigated antimicrobial resistance (AMR), virulence traits, and dissemination potential of E. coli from farmed foxes raised for fur production in northern China. From 248 fecal samples collected in Liaoning, Hebei, and Shandong, 109 E. coli isolates were recovered. We first performed phenotypic screening using four clinically important sentinel antibiotics (meropenem, polymyxin B, tigecycline, and ceftazidime) and then conducted in-depth characterization of the 34 screen-positive isolates, including extended susceptibility testing, PCR detection of resistance/virulence genes, conjugation assays, biofilm quantification, and whole-genome sequencing of 25 representative isolates. The screen-positive isolates showed widespread multidrug resistance and a diverse resistome; transfer of resistance determinants was observed in a subset of isolates. Targeted virulence screening detected only six virulence gene targets (irp2, fimH, fimC, fyuA, astA, and invE), and selected representative strains reduced survival in the Galleria mellonella infection model at high inocula. Biofilm formation varied across isolates, with a subset exhibiting strong biofilm-forming capacity. Whole-genome analysis further revealed abundant resistance determinants, virulence factors, and mobile genetic element–associated genes, highlighting the potential for persistence and dissemination within farm environments. Collectively, these findings provide an integrated view of AMR and virulence features of fox-derived E. coli and support ongoing surveillance and risk-mitigation efforts in fur-animal production systems.
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