Evidence map›Paper›PMID 41902941›Full record

ReviewArchives of microbiology2026

Fungal cellulases: a comprehensive review on production, innovations, and applications.

Mahima, Varsha Rani, Kunwar Vishal, Pawan Kumar Doharey, Aiman Tanveer, Pramod K Yadav, Dinesh Yadav

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mahima *Department of Biotechnology, Deen Dayal Upadhyaya Gorakhpur University, Gorakhpur, Uttar Pradesh, 273 009, India.
Varsha Rani *Department of Biotechnology, School of Engineering and Technology, Sandip University, Nashik, Maharashtra, 422213, India.
Kunwar VishalDepartment of Life Sciences and Biotechnology, Chhatrapati Shahu Ji Maharaj University, Kanpur, Uttar Pradesh, 208024, India.
Pawan Kumar DohareyDepartment of Biotechnology, Deen Dayal Upadhyaya Gorakhpur University, Gorakhpur, Uttar Pradesh, 273 009, India.
Aiman TanveerInstitute of Agriculture and Natural Sciences, Deen Dayal Upadhyaya Gorakhpur University, Gorakhpur, Uttar Pradesh, 273 009, India.
Pramod K YadavDepartment of Life Sciences and Biotechnology, Chhatrapati Shahu Ji Maharaj University, Kanpur, Uttar Pradesh, 208024, India.
Dinesh YadavDepartment of Biotechnology, Deen Dayal Upadhyaya Gorakhpur University, Gorakhpur, Uttar Pradesh, 273 009, India. dinesh.biotech@ddugu.ac.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal cellulases are pivotal industrial enzymes with diverse applications across agriculture, textiles, biofuels, and bioremediation. It belongs to Carbohydrate-Active Enzymes (CAZy) families such as GH5, GH6, and GH7, which are primarily produced by filamentous fungi like Trichoderma, Aspergillus, and Penicillium. These enzymes exhibit high stability and efficiency, making them superior to plant and animal-derived counterparts. The review explores production strategies, including solid-state and submerged fermentation, highlighting their advantages and challenges. It also discusses the use of agricultural and industrial waste as cost-effective substrates, aligned with the principles of the circular economy. Advanced techniques, such as directed evolution, nanotechnology-based immobilization, and omics-based approaches, have enhanced cellulase production and efficiency. Structural insights into fungal cellulases, including their catalytic domains and carbohydrate-binding modules, provide a foundation for understanding their catalytic mechanisms. Comparative analyses with bacterial cellulases reveal unique structural adaptations that influence substrate specificity and processivity. The industrial significance of fungal cellulases is emphasized by their role in biofuel production, textile processing, and bioremediation. Innovations in enzyme immobilization and recombinant expression further expand their applicability. This review aims to serve as a resource for researchers and industries seeking to harness the potential of fungal cellulases in sustainable bioprocessing and biotechnology.

Indexed as

CellulasesFungal ProteinsFungiBiodegradation, EnvironmentalBiofuelsBiotechnologyEnzymes, ImmobilizedFermentationSubstrate SpecificityBiofuelsCellulasesEnzymes, ImmobilizedFungal ProteinsCatalytic domainsCAZy familiesCellulaseDirected evolutionEnzyme immobilizationFungal cellulasesLPMONext generation cellulasesOmicsStatistical optimization

Identifiers

PMID41902941

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.