Evidence map›Paper›PMID 41902909›Full record

ArticlePediatric nephrology (Berlin, Germany)2026

Lung ultrasound: a complementary dynamic method to estimate target weight in pediatric hemodialysis.

Benjamin Moussler, Arnaud Wiedemann, Anne Mirguet, Marie-Christine Camoin-Schweitzer, Amandine Luc, Elodie Jeanbert, Isabelle Vrillon, Chloé Grosyeux

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Article in Pediatric nephrology (Berlin, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Benjamin MousslerPediatric Nephrology Department, University Hospital of Nancy, Nancy, 54000, France. b.moussler2@chru-nancy.fr.ORCID http://orcid.org/0009-0002-0876-9992
Arnaud WiedemannPediatric Intensive Care Unit, University Regional Hospital Center of Nancy, Nancy, F-54000, France.
Anne MirguetPediatric Nephrology Department, University Hospital of Nancy, Nancy, 54000, France.
Marie-Christine Camoin-SchweitzerPediatric Nephrology Department, University Hospital of Nancy, Nancy, 54000, France.
Amandine LucDRCI, MPI Department, Methodology, Data Management and Statistics Unit, University Hospital of Nancy, Nancy, France.
Elodie JeanbertDRCI, MPI Department, Methodology, Data Management and Statistics Unit, University Hospital of Nancy, Nancy, France.
Isabelle VrillonPediatric Nephrology Department, University Hospital of Nancy, Nancy, 54000, France.
Chloé GrosyeuxPediatric Nephrology Department, University Hospital of Nancy, Nancy, 54000, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTarget weight assessment remains challenging, particularly in children, where ongoing growth adds complexity. Lung ultrasound (LUS) has emerged as a promising tool for assessing hydration, although pediatric data are limited.

methodsWe conducted a retrospective, single-center study between January and September 2024. Target weight was assessed using clinical examination, pre-dialysis NT-proBNP level, relative overhydration by bioimpedance analysis (BIA), inferior vena cava (IVC) diameter, and LUS score (12-zone protocol). The primary outcome was the association between LUS and other assessment methods. Secondary outcomes included the reliability of LUS with dialysis-related weight loss and its contribution to multimodal evaluation. Mixed-effects regression models were used.

resultsSixty-eight dialysis sessions of 10 children on hemodialysis were analyzed. The median pre-dialysis LUS score was 7 (IQR 5-9), which decreased to 4 (IQR 3-6) post-dialysis. LUS correlated significantly with NT-proBNP level (p = 0.006) but not with BIA or IVC. A trend was observed for clinical signs (p = 0.072). Changes in the LUS score correlated with dialysis-related weight loss (p < 0.001).

conclusionsLUS is a sensitive, dynamic complementary tool for assessing target weight in pediatric hemodialysis patients. It provides additional information on extravascular fluid status and should be considered within multimodal target weight strategies, especially in cases of discordance.

Indexed as

Body WeightKidney Failure, ChronicLungRenal DialysisAdolescentChildChild, PreschoolElectric ImpedanceFemaleHumansMaleNatriuretic Peptide, BrainPeptide FragmentsReproducibility of ResultsRetrospective StudiesUltrasonographyNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)Biompedance spectroscopyHemodialysisInferior vena cavaLung ultrasoundNT-proBNPPediatricsTarget weight

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.