ArticleAging clinical and experimental research2026
Validation of the Charité Mobility assessment (CHARMI) in older adults across a wide range of functional levels - the prospective longitudinal MobiTest cohort study.
Article in Aging clinical and experimental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundComprehensive mobility assessment is crucial in geriatrics, yet existing tools may lack feasibility, or applicability for older adults with varying functional levels.
aimsWe evaluated the construct validity, interrater reliability, responsiveness, and minimal important change (MIC) of the Charité Mobility Index (CHARMI), in older adults.
methodsA prospective longitudinal cohort study was conducted with older adults ≥ 70y undergoing rehabilitation in acute care, inpatient or outpatient rehabilitation. CHARMI assessments were performed at admission and discharge and correlated with established mobility measures – the De Morton Mobility Index (DEMMI), Short Physical Performance Battery (SPPB), Timed Up and Go (TUG), and Barthel Index (BI) mobility items. Construct validity and responsiveness were evaluated using a hypothesis-testing approach based on a priori-hypotheses; interrater reliability (IRR) was assessed in a subsample. The MIC was determined in an anchor-based approach via ROC analysis.
results93 participants (mean age 82.8y) were included. Evidence for validity was supported by meeting 7 of 8 a priori hypotheses including strong correlations with DEMMI and SPPB and a moderate inverse correlation with TUG. IRR was 0.97 (95% CI: 0,91; 0,99). Evidence for responsiveness was supported by meeting 6 of 8 a priori hypotheses. The MIC was established at 1.5 CHARMI points. DISCUSSION AND
conclusionsThis study provides evidence supporting the CHARMI as a valid, responsive and reliable outcome measure with a useful MIC, making it a valuable option for tracking mobility in older adults across different settings and timepoints. Further studies should confirm generalizability and evaluate feasibility.
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