ArticleVeterinary research communications2026
Application of infrapatellar fat pad-derived stem cells after surgical reconstruction of a ruptured cranial cruciate ligament in a dog.
Article in Veterinary research communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Adipose-derived stem cells (ASCs) have been utilized in regenerative and anti-inflammatory therapies. Among the various sources of ASCs, infrapatellar fat pad-derived adipose stem cells (IFP-ASCs) have been proposed as an alternative source for treating orthopedic diseases in humans; however, their clinical application remains limited. Furthermore, clinical reports on the use of IFP-ASCs are scarce in veterinary medicine. The present report describes the first clinical application of IFP-ASCs in a dog following surgical reconstruction of a ruptured cranial cruciate ligament (CCL). After intra-articular injections of IFP-ASCs adjunctive to surgical stabilization, reductions in inflammatory cytokine levels and improvements in clinical orthopedic scores were observed without any adverse effects. This case suggests that autologous IFP-ASC treatment after surgical CCL reconstruction may be a safe and effective adjunctive treatment for canine joint disorders.
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