ArticleJACC. Case reports2026
The Snubbed Complication: Why Postinfarction Ventricular Septal Defect Management Lacks Evidence-Based Guidance in 2026.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Stabilize, Delay, or Intervene?: Management of Postinfarction Septal Rupture With Limited Evidence.JACC. Case reports · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe management of postinfarction ventricular septal defect (VSD) is contentious, especially when complicated by cardiogenic shock and concomitant severe aortic stenosis, with no clear guidelines. CASE SUMMARY: A 73-year-old woman presented with cardiogenic shock due to a large postinfarction VSD (Q DISCUSSION: Three management strategies were initially considered: Viewpoint 1 advocated for immediate combined surgery (VSD repair, aortic valve replacement, coronary artery bypass grafting), arguing for a definitive, single-stage correction given the patient's profile. Viewpoint 2 proposed venoarterial extracorporeal membrane oxygenation as a bridge to delayed surgery, prioritizing stabilization and tissue healing to reduce the high risk of operating on acute, friable myocardium. Viewpoint 3 deemed surgery and extracorporeal membrane oxygenation prohibitively risky, favoring a staged transcatheter approach (balloon valvuloplasty followed by VSD closure) to circumvent the morbidity of open surgery. TAKE-HOME MESSAGES: Postinfarction VSD management requires urgent, multidisciplinary consensus. All strategies carry significant risks, and percutaneous solutions are limited by tissue friability in the acute phase.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.