Evidence map›Paper›PMID 41902704›Full record

ArticleJournal of obesity2026

Association Between Metabolic and Endocrine Parameters With Visceral Adiposity Index-Defined Adipose Tissue Dysfunction in Young Adult Males.

Gabriela Yuri, Natalia Santillana, Liliana Soto, Ana Pereira, Camila Corvalán, Mariana Cifuentes

Abstract read
In one paragraph

Article in Journal of obesity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gabriela YuriInstitute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile, uchile.cl.ORCID 0000-0002-3706-8637
Natalia SantillanaInstitute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile, uchile.cl.ORCID 0000-0002-1523-151X
Liliana SotoInstitute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile, uchile.cl.ORCID 0009-0003-0151-8549
Ana PereiraInstitute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile, uchile.cl.ORCID 0000-0003-1587-4264
Camila CorvalánInstitute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile, uchile.cl.ORCID 0000-0003-3766-7709
Mariana CifuentesInstitute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile, uchile.cl.ORCID 0000-0001-9485-3490

Funding

Beca Doctorado Nacional 21220077Beca Doctorado Nacional 212304016Fondap Apoyo Program 1523A0008Fondap Program 15130011Fondo Nacional de Desarrollo Científico y Tecnológico 1211477Fondo Nacional de Desarrollo Científico y Tecnológico 1230813
6 · The paper itself

Abstract

backgroundOverweight and obesity are defined by body mass index (BMI); however, this indicator does not address the wide variability that exists in metabolic health for a given BMI. This largely depends on adipose tissue functionality and location, with larger visceral depots elevating inflammation and cardiometabolic risk. The visceral adiposity index (VAI) provides a closer approach to adipose tissue functionality; however, there are limited studies addressing its ability to identify differences in metabolic health among young adults with excess weight. We evaluated whether low versus high VAI (L-VAI vs. H-VAI) groups differ in body composition, endocrine and metabolic indicators, and indices of metabolic risk and adipose tissue function.

methodsFifty-two healthy adult males with BMI ≥ 25 kg/m

resultsSubjects in the H-VAI group (∼40%) showed greater truncal fat mass and lower adiponectin/leptin ratio (Ad/Lep), as well as greater indices of insulin resistance (HOMA-IR and triglyceride/glucose) and the metabolic syndrome severity score. Significant positive correlations were found between VAI and the cardiovascular risk and metabolic syndrome-related factors, plasminogen activator inhibitor-1 (PAI-1), uric acid, and HOMA-IR and an inverse association with adiponectin and Ad/Lep.

conclusionsOur observations indicate that VAI is a useful tool to assess cardiometabolic risk and adipose tissue functionality in young adult males with overweight and obesity.

Indexed as

AdiposityIntra-Abdominal FatObesity, AbdominalAdiponectinAdultBody CompositionBody Mass IndexCross-Sectional StudiesHumansInsulin ResistanceMaleMetabolic SyndromeYoung AdultAdiponectinbody compositionmetabolic syndromevisceral adipose tissue

Identifiers

PMID41902704
PMCPMC13140360

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.