ArticleJournal of neurophysiology2026
Positive association between local brain hypercorrelations and posttraumatic stress disorder symptom severity.
Article in Journal of neurophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Previous studies have documented neural network anomalies in posttraumatic stress disorder (PTSD) characterized by hypercorrelated interactions across brain areas, relative to controls. Here, we evaluated and compared local, intra-area(s), interactions by computing cross-correlations derived from prewhitened resting-state 3 T fMRI BOLD time series within 84 brain regions (35 cortical areas and 7 subcortical nuclei per hemisphere) in 15 veterans with PTSD and 21 healthy controls. We found that intra-area correlations were significantly higher in PTSD, as compared with controls, indicating a restriction in local network flexibility. PTSD symptom severity was positively and significantly associated with increased local correlations, most prominently in frontal and limbic areas.
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