ReviewHeadache2026
Reversible cerebral vasoconstriction syndrome: A narrative review.
Review in Headache, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
OBJECTIVES/
backgroundThis review summarizes current insights into Reversible cerebral vasoconstriction syndrome (RCVS) diagnosis, management, and outcomes. RCVS is a cerebrovascular disorder characterized by recurrent thunderclap headaches and transient segmental vasoconstriction of cerebral arteries, typically resolving within 3 months.
methodsA comprehensive database search was performed across MEDLINE (via PubMed), Embase, Scopus, and the Cochrane Library.
resultsAlthough often self-limiting, RCVS may cause complications such as subarachnoid hemorrhage, ischemic stroke, and cerebral edema. Triggers include vasoactive substances, pregnancy, postpartum state, and physical or emotional stress. Differentiating RCVS from conditions like primary angiitis of the central nervous system, aneurysmal subarachnoid hemorrhage, and cerebral venous thrombosis is essential because clinical and imaging features may overlap, whereas treatments differ. Advances in neuroimaging, especially magnetic resonance angiography and vessel wall imaging, have enhanced diagnostic accuracy. Management focuses on eliminating triggers and symptomatic support. Calcium channel blockers are frequently used, although their impact on disease evolution remains uncertain.
conclusionAlthough most patients recover without major sequelae, chronic symptoms such as long-term headaches and neuropsychological symptoms, including cognitive impairment, underscore the need for ongoing follow-up and suggest a post-RCVS syndrome.
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Registered trials
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