Evidence map›Paper›PMID 41902429›Full record

ArticleHeadache2026

Chronotype in migraine and tension-type headache: A population study.

Da Eun Jung, Soomi Cho, Woo-Seok Ha, Hye Jung Shin, Min Kyung Chu

Abstract read
In one paragraph

Article in Headache, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Da Eun JungDepartment of Neurology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0009-0008-2082-9138
Soomi ChoDepartment of Neurology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0003-4723-8975
Woo-Seok HaDepartment of Neurology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0003-1188-449X
Hye Jung ShinBiostatistics Collaboration Unit, Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0001-5346-7278
Min Kyung ChuDepartment of Neurology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0001-6221-1346

Funding

National Research Foundation of Korea 2022R1A2C1091767Severance Hospital Research fund for Clinical excellence (SHRC) C-2025-0017The Korea Health Technology R&D Project through the Korea Health Industry Development Institute HV22C0106
6 · The paper itself

Abstract

objectivesThis study was designed to examine the distribution of chronotypes among individuals with migraine and tension-type headache and to evaluate the association between chronotype and clinical headache characteristics in a population-based sample.

backgroundAlthough previous research has demonstrated associations between chronotype and migraine, there is limited population-level evidence regarding its relationship with tension-type headache or clinical features of these headache disorders.

methodsWe conducted a cross-sectional analysis using baseline data from a nationwide population-based survey, conducted in the Republic of Korea in October 2020, which involved adults 20-59 years old. The chronotype was assessed using the Morningness-Eveningness Questionnaire and categorized into morning (score >58), intermediate (score 41-58), and evening (score <41) chronotypes.

resultsAmong 2838 participants, the evening chronotype was more prevalent in the migraine (58 of 160, 36.3%) and tension-type headache (225 of 890, 25.3%) groups than in the nonheadache control group (185 of 1005, 18.4%, p < 0.001). Among participants with migraine, depression (Patient Health Questionnaire-9) and anxiety (Generalized Anxiety Disorder-7) differed across chronotypes in the overall comparison (p = 0.035 and p = 0.047, respectively), with the morning type showing lower levels than those shown by the intermediate and evening types; however, no pairwise differences were statistically significant in the post hoc analyses. Among participants with tension-type headache, depression and anxiety differed across chronotypes in the overall comparison (Patient Health Questionnaire-9, p < 0.001 and Generalized Anxiety Disorder-7, p = 0.006), which was driven by higher levels in the evening type than in both the morning and intermediate types; however, the morning and intermediate types did not differ. In participants with migraine, a higher Morningness-Eveningness Questionnaire score (greater morningness) was marginally associated with more severe headache days per 30 days (p = 0.046), whereas no significant association was found in those with tension-type headache (p = 0.126). Headache days per 30 days, crystal-clear days per 30 days, headache intensity (Visual Analog Scale), and the impact of headache (Headache Impact Test-6) were not significantly associated with Morningness-Eveningness Questionnaire scores in participants with migraine or tension-type headache.

conclusionParticipants with migraine and tension-type headache showed a significantly higher prevalence of evening chronotype compared with the nonheadache controls. However, greater morningness was associated with more severe headache days in the migraine group but not in the tension-type headache group.

Indexed as

ChronotypeCircadian RhythmMigraine DisordersTension-Type HeadacheAdultCross-Sectional StudiesDepressionFemaleHumansMaleMiddle AgedRepublic of KoreaSurveys and QuestionnairesYoung Adultchronobiology disordersheadache disordermigraine disordermood disorderssleep wake disorders

Identifiers

PMID41902429
PMCPMC13142205

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.