Evidence map›Paper›PMID 41902297›Full record

ReviewViruses2026

Mechanisms of APOBEC3 Packaging into HIV-1.

Mirriam Nzivo, Christoph G W Gertzen, Tom Luedde, Holger Gohlke, Carsten Münk

Abstract readReview
In one paragraph

Review in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mirriam NzivoClinic of Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty, Heinrich Heine University Düsseldorf, 40225 Duesseldorf, Germany.
Christoph G W GertzenInstitute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, 40225 Duesseldorf, Germany.
Tom LueddeClinic of Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty, Heinrich Heine University Düsseldorf, 40225 Duesseldorf, Germany.ORCID 0000-0002-6288-8821
Holger GohlkeInstitute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, 40225 Duesseldorf, Germany.ORCID 0000-0001-8613-1447
Carsten MünkClinic of Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty, Heinrich Heine University Düsseldorf, 40225 Duesseldorf, Germany.ORCID 0000-0002-8026-9311

Funding

Deutsche Forschungsgemeinschaft 417919780, INST 208/761-1 FUGGGerman Academic Exchange Service 91833372Heinz Ansmann Foundation n/aHIV Research TRUST n/a
6 · The paper itself

Abstract

Apolipoprotein B mRNA editing enzyme catalytic polypeptide 3s (APOBEC3s, A3s) are single-stranded DNA cytidine deaminases with antiviral activity against diverse DNA and RNA viruses. The human APOBEC3 locus encodes seven members: A3A, A3B, A3C, A3D, A3F, A3G, and A3H. Of these, A3C, A3D, A3F, A3G, and A3H are packaged into HIV-1, lacking the viral infectivity factor (VIF, HIV-1Δ

Indexed as

Cytidine DeaminaseHIV-1HIV InfectionsVirus AssemblyAPOBEC DeaminasesHumansRNA, ViralVirionAPOBEC3 proteins, humanAPOBEC DeaminasesCytidine DeaminaseRNA, ViralAPOBEC3sGAGHIV-1packagingRNAs

Identifiers

PMID41902297
PMCPMC13030881

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.