Evidence map›Paper›PMID 41902248›Full record

Observational studyViruses2026

Neurological Signs and Symptoms in Human T-Lymphotropic Viruses 1 and 2 Infected Patients Living in the Amazon Region, Northern Brazil.

Giovani Camelo do Nascimento, Lucas Thiago Ferreira Monteiro, Hemengella Karyne Alves Oliveira, Márcio Yutaka Tsukimata, Bianca Lumi Inomata da Silva, Aline Cecy Rocha Lima, Rodrigo Borges de Oliveira, Gabriel Dos Santos Pereira Neto, Eduardo Leitão Maia, Ricardo Ishak and 2 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Giovani Camelo do NascimentoLaboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 66.075-110, Brazil.
Lucas Thiago Ferreira MonteiroFaculdade de Medicina, Instituto de Ciências Médicas, Universidade Federal do Pará, Belém 66.075-110, Brazil.
Hemengella Karyne Alves OliveiraFaculdade de Medicina, Instituto de Ciências Médicas, Universidade Federal do Pará, Belém 66.075-110, Brazil.
Márcio Yutaka TsukimataLaboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 66.075-110, Brazil.ORCID 0000-0003-2916-4036
Bianca Lumi Inomata da SilvaLaboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 66.075-110, Brazil.
Aline Cecy Rocha LimaLaboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 66.075-110, Brazil.
Rodrigo Borges de OliveiraFaculdade de Medicina, Instituto de Ciências Médicas, Universidade Federal do Pará, Belém 66.075-110, Brazil.ORCID 0009-0009-6443-6720
Gabriel Dos Santos Pereira NetoLaboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 66.075-110, Brazil.
Eduardo Leitão MaiaHospital Universitário João de Barros Barreto, Belém 66.073-000, Brazil.
Ricardo IshakLaboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 66.075-110, Brazil.
Antonio Carlos Rosário VallinotoLaboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 66.075-110, Brazil.ORCID 0000-0003-1135-6507
Izaura Maria Vieira Cayres VallinotoLaboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 66.075-110, Brazil.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico #302935/2021-5, #304835/2022-6, #303837/2023-3, #401569/2023-3, #405625/2025-1 and #402478/2025-8
6 · The paper itself

Abstract

HTLV-1 and HTLV-2 infections are associated with various neurological manifestations, particularly HTLV-1-associated myelopathy (HAM). This descriptive, cross-sectional observational study aimed to investigate and analyze the neurological manifestations in patients treated at the Service for the Care of People Living with HTLV (Serviço de Atendimento à Pessoa Vivendo com HTLV-SAPEVH) at the Federal University of Pará. A cohort of 957 individuals underwent screening for HTLV-1/2 infection using enzyme-linked immunosorbent assay (ELISA), with seropositive samples subsequently confirmed via Western blotting or quantitative polymerase chain reaction (qPCR). HTLV-1/2 infection was confirmed in 69 individuals. Of these, fifteen individuals-diagnosed with HTLV-1 (

Indexed as

HTLV-II InfectionsHTLV-I InfectionsHuman T-lymphotropic virus 1Human T-lymphotropic virus 2Nervous System DiseasesAdultAgedAged, 80 and overBrazilCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayFemaleHumansMaleMiddle Agedclinical markersHAMHTLV-1HTLV-2neuropathology

Identifiers

PMID41902248
PMCPMC13030128

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.