Evidence map›Paper›PMID 41902202›Full record

ArticleViruses2026

Genomic Characterization of the Index Case of Human Monkeypox Virus Infection in Mali, 2025.

Noumou Yakhouba Keita, Mahamadou Abdou, Mohamed Ag Baraïka, Klema Marcel Kone, Ousmane Kamena, Elysabette Coulibaly, Mariam Sama Sangare, Korika Diakite, Dorcas Waruguru Wanjohi, Boubacar Doumbia and 3 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Noumou Yakhouba KeitaInstitut National de Santé Pulique, Hippodrome Route de Koulikoro Rue 235 Porte 52, Bamako BP 1771, Mali.ORCID 0000-0001-7138-6164
Mahamadou AbdouInstitut National de Santé Pulique, Hippodrome Route de Koulikoro Rue 235 Porte 52, Bamako BP 1771, Mali.
Mohamed Ag BaraïkaInstitut National de Santé Pulique, Hippodrome Route de Koulikoro Rue 235 Porte 52, Bamako BP 1771, Mali.
Klema Marcel KoneInstitut National de Santé Pulique, Hippodrome Route de Koulikoro Rue 235 Porte 52, Bamako BP 1771, Mali.ORCID 0000-0002-8008-3517
Ousmane KamenaInstitut National de Santé Pulique, Hippodrome Route de Koulikoro Rue 235 Porte 52, Bamako BP 1771, Mali.ORCID 0009-0005-8868-9483
Elysabette CoulibalyInstitut National de Santé Pulique, Hippodrome Route de Koulikoro Rue 235 Porte 52, Bamako BP 1771, Mali.
Mariam Sama SangareInstitut National de Santé Pulique, Hippodrome Route de Koulikoro Rue 235 Porte 52, Bamako BP 1771, Mali.
Korika DiakiteInstitut National de Santé Pulique, Hippodrome Route de Koulikoro Rue 235 Porte 52, Bamako BP 1771, Mali.
Dorcas Waruguru WanjohiAfrica Centres for Disease Control and Prevention (Africa CDC), Addis Ababa P.O. Box 3243, Ethiopia.
Boubacar DoumbiaInstitut National de Santé Pulique, Hippodrome Route de Koulikoro Rue 235 Porte 52, Bamako BP 1771, Mali.
Harris OnyweraAfrica Centres for Disease Control and Prevention (Africa CDC), Addis Ababa P.O. Box 3243, Ethiopia.ORCID 0000-0002-7298-4921
Moussa Moise DiagneInstitut Pasteur de Dakar, Dakar BP 220, Senegal.ORCID 0000-0001-5461-5623
Ibrehima GuindoInstitut National de Santé Pulique, Hippodrome Route de Koulikoro Rue 235 Porte 52, Bamako BP 1771, Mali.ORCID 0000-0003-3130-4763

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mpox is a zoonosis caused by the monkeypox virus. Here, we report Mali's index Mpox case, which was clinically identified at the Mali-Guinea border by the national telemedicine center and confirmed by PCR. The library prepared with NextGenPCR™ MPXV Sequencing Library Prep and sequenced on Minion MK1C revealed a genome length of 197,122 bp with an average depth of 1284.4×. The strain belonged to Clade IIb G1 lineage and exhibited 85 mutations relative to NC_063383.1. To decipher genomic epidemiology, genomes ≥ 195 kb were retrieved from NCBI and aligned with MAFFT. Time-resolved phylogenetic reconstruction and ancestral trait inference were performed with TreeTime v0.11.4. A median joining network was built with Popart v1.7. Phylogeographic analysis revealed clustering with Clade IIb (G.1 lineage) linked to the May 2025 outbreak in Sierra Leone.

Indexed as

Genome, ViralMonkeypox virusMpox, MonkeypoxAdultGenomicsHumansMaleMaliPhylogenyPhylogeographySequence Analysis, DNAemerginggenomeindexMalimonkeypox virusMpoxoutbreak

Identifiers

PMID41902202
PMCPMC13030366

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.