Evidence map›Paper›PMID 41902198›Full record

ArticleViruses2026

A High-Throughput Antiviral Assay Based on a Sindbis Virus-GFP for the Discovery of Inhibitors of Alphavirus Replication.

Gabriel Augusto Pires de Souza, Rana Abdelnabi, Bert Vanmechelen, Leni Van Eyck, Nelleke Cloet, Deniz Öner, Dirk Roymans, Aleksandra Siekierska, Koert Stittelaar, Johan Neyts

Abstract read
In one paragraph

Article in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gabriel Augusto Pires de SouzaVirusBank Platform, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0002-2479-4429
Rana AbdelnabiVirusBank Platform, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0001-9771-7312
Bert VanmechelenVirusBank Platform, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0002-8350-4356
Leni Van EyckVirusBank Platform, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, 3001 Leuven, Belgium.
Nelleke CloetVirusBank Platform, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, 3001 Leuven, Belgium.
Deniz ÖnerVirusBank Platform, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, 3001 Leuven, Belgium.
Dirk RoymansVirusBank Platform, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, 3001 Leuven, Belgium.
Aleksandra SiekierskaVirusBank Platform, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0003-4907-605X
Koert StittelaarVirusBank Platform, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0002-0607-3214
Johan NeytsVirusBank Platform, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0002-0033-7514

Funding

This work was supported by the Belgian Federal Government for the VirusBank Platform (FOD VVVL) NA
6 · The paper itself

Abstract

The re-emergence of alphaviruses (family

Indexed as

AlphavirusAntiviral AgentsHigh-Throughput Screening AssaysSindbis VirusVirus ReplicationAlphavirus InfectionsAnimalsCell LineChikungunya virusDrug DiscoveryDrug Evaluation, PreclinicalGenes, ReporterGreen Fluorescent ProteinsHumansReproducibility of ResultsAntiviral AgentsGreen Fluorescent Proteinsalphavirusantiviral screeningchikungunya virusemerging viruseshigh-throughput screeningSindbis virus

Identifiers

PMID41902198
PMCPMC13030731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.