Evidence map›Paper›PMID 41901791›Full record

ArticlePathogens (Basel, Switzerland)2026

Molecular Epidemiology of Toscana Virus in Northern and Central Italy Using Metagenomic Next-Generation Sequencing.

Giulia Alessandri, Giada Beligni, Gianni Gori Savellini, Alessandra Mistral De Pascali, Federica Gobbo, Fabrizio Montarsi, Davide Mileto, Letizia Rizzo, Maria Grazia Cusi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Giulia AlessandriVirology Unit, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Giada BeligniVirology Unit, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Gianni Gori SavelliniVirology Unit, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-2287-9258
Alessandra Mistral De PascaliDepartment of Surgical and Neuronal Sciences, Alma Mater Studiorum, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-8662-0782
Federica GobboLaboratorio di Entomologia Sanitaria e Patogeni Trasmessi da Vettori, Istituto Zooprofilattico Sperimentale delle Venezie, Viale del Università 10, 35020 Legnaro, Italy.ORCID 0000-0001-9233-5737
Fabrizio MontarsiLaboratorio di Entomologia Sanitaria e Patogeni Trasmessi da Vettori, Istituto Zooprofilattico Sperimentale delle Venezie, Viale del Università 10, 35020 Legnaro, Italy.ORCID 0000-0002-5004-5763
Davide MiletoSC Microbiologica Clinica, Virologia e Diagnostica Bioemergenze, ASST Fatebenefratelli Sacco, Polo Universitario "L. Sacco", Via G.B. Grassi 74, 20157 Milano, Italy.ORCID 0000-0002-9414-0287
Letizia RizzoVirology Unit, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Maria Grazia CusiVirology Unit, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0001-8869-8164

Funding

Ministero dell'Università e della Ricerca, Progetti di Rilevante Interesse Nazionale PRIN2022 PNRR P2022WYNAHNextGeneration EU-MUR PNRR Extended Partnership Initiative on Emerging Infectious Diseases INF-ACT PE00000007
6 · The paper itself

Abstract

Toscana virus (TOSV) is an arthropod-borne virus, transmitted by sandflies, which represents a major cause of aseptic meningitis in Mediterranean countries during summer months. Despite its epidemiological importance, recent genomic data on circulating Italian strains remain limited. We performed comprehensive phylogenetic and genotypic characterization of 34 TOSV isolates (32 obtained from human biological samples and 2 from sandfly homogenates) collected between 2022 and 2025 from Northern/Central Italy. All the sequenced isolates clustered within Lineage A, with strains circulating in Tuscany showing significantly lower intra group genetic divergence (

Indexed as

Bunyaviridae InfectionsMetagenomicsSandfly fever Naples virusAnimalsGenetic VariationGenome, ViralGenotypeHigh-Throughput Nucleotide SequencingHumansItalyMolecular EpidemiologyPhylogenyPhylogeographyPsychodidaemNGSphylogenetic analysisToscana virus

Identifiers

PMID41901791
PMCPMC13029180

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.