Evidence map›Paper›PMID 41901776›Full record

ArticlePathogens (Basel, Switzerland)2026

Evaluation of a Commercial Ozonated Olive Oil Product (800 mEq O

Hilke Oltmanns, Aimara Bello Suarez-Kupka, Christina Puff, Jessica Meißner, Andrea Vanessa Volk

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hilke OltmannsDepartment of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine Hannover Foundation, 30559 Hannover, Germany.ORCID 0000-0003-0596-4979
Aimara Bello Suarez-KupkaHospital for Small Animals, University of Veterinary Medicine Hannover Foundation, 30559 Hannover, Germany.
Christina PuffDepartment of Pathology, University of Veterinary Medicine Hannover Foundation, 30559 Hannover, Germany.ORCID 0000-0002-2592-6868
Jessica MeißnerDepartment of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine Hannover Foundation, 30559 Hannover, Germany.ORCID 0000-0002-7263-848X
Andrea Vanessa VolkHospital for Small Animals, University of Veterinary Medicine Hannover Foundation, 30559 Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMethicillin-resistant

objectiveWe aimed to evaluate the efficacy of commercial ozonated olive oil product (800 mEq O MATERIALS AND

methodsIn vitro susceptibility testing determined minimum inhibitory concentrations (MIC) and time-kill kinetics. Subsequently, canine skin samples were mounted in Franz diffusion cells, inoculated with MRSP (~10

resultsIn vitro testing demonstrated antibacterial activity for ozonated oil (MIC < 20%

conclusionsDespite in vitro activity, this ozonated olive oil failed to reduce MRSP in ex vivo skin, revealing that tissue barriers prevent antibacterial delivery. These findings demonstrate that in vitro screening cannot predict topical efficacy and emphasize the necessity of tissue-based validation before clinical use.

Indexed as

Anti-Bacterial AgentsOlive OilOzoneSkinStaphylococcusAnimalsDogsMethicillin ResistanceMicrobial Sensitivity TestsMicrobial ViabilityAnti-Bacterial AgentsOlive OilOzoneantibacterial therapycanineex vivo skin modelFranz diffusion cellMRSPozonated oil

Identifiers

PMID41901776
PMCPMC13029303

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.