Evidence map›Paper›PMID 41901774›Full record

ArticlePathogens (Basel, Switzerland)2026

A Fatal Case of Puumala Virus Infection with Pulmonary and Renal Syndrome in Moscow Region, Russia.

Ekaterina Blinova, Tamara Dzagurova, Galina Gopatsa, Natalya Pshenichnaya, Evgeny Morozkin, Vasiliy Akimkin

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ekaterina BlinovaFederal Budget Institute of Science «Central Research Institute of Epidemiology», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, 111123 Moscow, Russia.
Tamara DzagurovaChumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products, Russian Academy of Sciences (Institute of Poliomyelitis), 117218 Moscow, Russia.
Galina GopatsaFederal Budget Institute of Science «Central Research Institute of Epidemiology», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, 111123 Moscow, Russia.
Natalya PshenichnayaFederal Budget Institute of Science «Central Research Institute of Epidemiology», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, 111123 Moscow, Russia.
Evgeny MorozkinFederal Budget Institute of Science «Central Research Institute of Epidemiology», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, 111123 Moscow, Russia.ORCID 0000-0001-8407-2623
Vasiliy AkimkinFederal Budget Institute of Science «Central Research Institute of Epidemiology», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, 111123 Moscow, Russia.ORCID 0000-0003-4228-9044

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemorrhagic fever with renal syndrome (HFRS) is the most common zoonotic disease in Russia, with about a 98% abundance of Puumala virus in all HFRS cases. We report clinical manifestations and genomic characteristics of the Puumala virus strain that caused an unconventional course of HFRS with sudden death. The patient was admitted to the hospital on the third day from fever onset with hyperthermia, cough, shortness of breath, and severe weakness, and died 28 h after hospitalization despite intensive care. Further analyses of autopsy samples led to Puumala virus detection. The viral genome was sequenced, followed by phylogenetic and similarity plot analyses. The genomic sequences of three viral segments were identified as endemic for the Moscow region strain. Phylogenetic and similarity plot analysis revealed the reassortant origin of the strain via M segment exchange. This finding increases the explored molecular diversity of Puumala virus in the Central Federal District and underscores the need for heightened awareness of HFRS manifestations that deviate from regular clinical presentation.

Indexed as

Hemorrhagic Fever with Renal SyndromePuumala virusFatal OutcomeGenome, ViralHumansMoscowPhylogenyhemorrhagic fever with renal syndromePuumala virusreassortment

Identifiers

PMID41901774
PMCPMC13029655

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.