Evidence map›Paper›PMID 41901313›Full record

ReviewPharmaceuticals (Basel, Switzerland)2026

Is Brukinsa (Zanubrutinib) a Safer Bruton's Tyrosine Kinase (BTK) Inhibitor in Relapsed or Refractory Chronic Lymphocytic Leukemia? A Systematic Review and Meta-Analysis.

Helal F Hetta, Ayman Salama, Turki A Aljuaid, Yazan T Mojmami, Riyadh S Alotibi, Ahmed M Alqabaly, Nawaf A Aldosari, Sami A Alshahri, Walid I A Asiri, Raed S Alamri and 5 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Helal F HettaDivision of Microbiology, Immunology and Biotechnology, Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.ORCID 0000-0001-8541-7304
Ayman SalamaDepartment of Pharmaceutics, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.ORCID 0009-0005-7946-4477
Turki A AljuaidPharmD Program, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.
Yazan T MojmamiPharmD Program, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.
Riyadh S AlotibiPharmD Program, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.
Ahmed M AlqabalyPharmD Program, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.
Nawaf A AldosariPharmD Program, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.
Sami A AlshahriPharmD Program, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.
Walid I A AsiriPharmD Program, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.
Raed S AlamriPharmD Program, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.
Fayez A AlanaziPharmD Program, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.
Malek S A AlenaziPharmD Program, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.
Mohammed H AlbuhayriPharmD Program, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.
Yasmin N RamadanDepartment of Microbiology and Immunology, Faculty of Pharmacy, Assiut University, Assiut 71515, Egypt.ORCID 0009-0008-7374-9334
Reem SayadDepartment of Histology, Faculty of Medicine, Assiut University, Assiut 71515, Egypt.ORCID 0000-0002-4378-2714

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BGB-3111BrukinsaBruton’s tyrosine kinase inhibitorchronic lymphocytic leukemiarelapsed/refractorysmall lymphocytic lymphomazanubrutinib

Identifiers

PMID41901313
PMCPMC13028685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.