ArticlePharmaceuticals (Basel, Switzerland)2026
Harnessing Substituted 4-Chlorothieno[2,3-
Mostafa M Badran, Berkay Beyri, Hiroshi Tateishi, Kazunori Shimagaki, Akiko Nakata, Akihiro Ito, Nao Nishimura, Samar H Abbas, Mohamed Abdel-Aziz, Masami Otsuka and 4 more
Abstract read
In one paragraphArticle in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
Mostafa M BadranDepartment of Medicinal Chemistry, Faculty of Pharmacy, Qena University (Formerly South Valley University), Qena 83523, Egypt.ORCID 0000-0002-3295-1500 Berkay BeyriMedicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan.ORCID 0009-0002-9757-2250 Hiroshi TateishiMedicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan.ORCID 0000-0003-1225-0720 Kazunori ShimagakiMedicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan.
Akiko NakataDrug Discovery Seeds Development Unit, RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.ORCID 0000-0002-8451-680X Akihiro ItoDrug Discovery Seeds Development Unit, RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.ORCID 0000-0003-0908-8929 Nao NishimuraDepartment of Hematology, Rheumatology and Infectious Diseases, Kumamoto University Hospital, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-8556, Japan.
Samar H AbbasMedicinal Chemistry Department, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.ORCID 0000-0002-9586-2644 Mohamed Abdel-AzizMedicinal Chemistry Department, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.
Masami OtsukaMedicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan.
Minoru YoshidaDrug Discovery Seeds Development Unit, RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.ORCID 0000-0002-4376-5674 Mikako FujitaMedicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan.ORCID 0000-0001-6705-4052 Stefan BräseInstitute of Biological and Chemical Systems-Functional Molecular Systems (IBCS-FMS), Karlsruhe Institute of Technology (KIT), Kaisersrasse 12, 76131 Karlsruhe, Germany.ORCID 0000-0003-4845-3191 Mohamed O RadwanMedicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan.ORCID 0000-0002-9220-2659 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
[2,3-b]pyridine4-chlorothieno[2,3-b]pyridineanticancerHDAC inhibitorshydroxamic acidRPMI-8226 multiple myelomaVilsmier Haack
Identifiers
PMID41901290
PMCPMC13029047
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