Evidence map›Paper›PMID 41901222›Full record

ArticlePharmaceuticals (Basel, Switzerland)2026

The FAM111A Gene: Genetic, Epigenetic, and Pharmacological Targets and Mechanistic Insights with Clinical Relevance.

Kyriaki Hatziagapiou, Feneli Karachaliou, Trias Thireou, Eleni Koniari, Dimitrios Chaniotis, Apostolos Beloukas, Galateia Stathori, Panagiota Kafkaloudi, Bettina Krumbholz, George P Chrousos and 1 more

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kyriaki HatziagapiouUniversity Research Institute of Maternal and Child Health and Precision Medicine, School of Medicine, National Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-1469-1928
Feneli KarachaliouUnit of Pediatric Endocrinology, Metabolism and Diabetes, 3rd Department of Pediatrics, School of Medicine, National Kapodistrian University of Athens, 11528 Athens, Greece.
Trias ThireouLaboratory of Genetics, Department of Biotechnology, Agricultural University of Athens, 11855 Athens, Greece.ORCID 0000-0002-6894-0774
Eleni KoniariUniversity Research Institute of Maternal and Child Health and Precision Medicine, School of Medicine, National Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0009-0008-6294-1988
Dimitrios ChaniotisDepartment of Biomedical Sciences, University of West Attica, Agioy Spyridonos 28, 12243 Egaleo, Greece.ORCID 0000-0003-2313-1305
Apostolos BeloukasDepartment of Biomedical Sciences, University of West Attica, Agioy Spyridonos 28, 12243 Egaleo, Greece.ORCID 0000-0001-5639-0528
Galateia StathoriUniversity Research Institute of Maternal and Child Health and Precision Medicine, School of Medicine, National Kapodistrian University of Athens, 11527 Athens, Greece.
Panagiota KafkaloudiPrimary Healthcare Center of Amarousion, 15124 Athens, Greece.
Bettina KrumbholzPrimary Healthcare Center of Amarousion, 15124 Athens, Greece.
George P ChrousosUniversity Research Institute of Maternal and Child Health and Precision Medicine, School of Medicine, National Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-3098-5264
Louis PapageorgiouDepartment of Biomedical Sciences, University of West Attica, Agioy Spyridonos 28, 12243 Egaleo, Greece.ORCID 0000-0001-9577-9923

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antiviral restriction factorscatalytic triadconserved protein motifsDNA replication stressFAM111AKenny–Caffey syndrome type 2osteocraniostenosisreplication-fork protectionserine endopeptidasesserine protease domain

Identifiers

PMID41901222
PMCPMC13029412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.