Evidence map›Paper›PMID 41900963›Full record

ReviewLife (Basel, Switzerland)2026

Artificial Intelligence-Enhanced Telerehabilitation in Post-Acute Coronary Syndrome: A Narrative Review of Opportunities, Evidence, and Future Directions.

Alina Gherghin, Mircea Ioan Alexandru Bistriceanu, Ilie Onu, Daniel Andrei Iordan, Florentin Dimofte, Adriana Neofit, Dan Eugen Costin, Alexandru Scafa-Udriste

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alina GherghinDoctoral School, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0009-0004-3291-1391
Mircea Ioan Alexandru BistriceanuDoctoral School, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0009-0000-3361-2167
Ilie OnuDepartment of Biomedical Sciences, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700454 Iasi, Romania.ORCID 0000-0002-1003-0719
Daniel Andrei IordanCenter of Physical Therapy, Rehabilitation and Wellness, "Dunărea de Jos" University of Galati, 800008 Galati, Romania.ORCID 0000-0001-6422-2030
Florentin DimofteCenter of Physical Therapy, Rehabilitation and Wellness, "Dunărea de Jos" University of Galati, 800008 Galati, Romania.
Adriana NeofitCenter of Physical Therapy, Rehabilitation and Wellness, "Dunărea de Jos" University of Galati, 800008 Galati, Romania.
Dan Eugen CostinCenter of Physical Therapy, Rehabilitation and Wellness, "Dunărea de Jos" University of Galati, 800008 Galati, Romania.
Alexandru Scafa-UdristeDoctoral School, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0003-3207-1025

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac telerehabilitation has become a promising alternative to traditional programmes for preventing acute coronary syndrome (ACS) in the secondary phase. However, current implementations are still reactive and standardised, lacking personalisation and flexibility in clinical settings. By integrating artificial intelligence (AI), it may be possible to overcome these limitations and provide intelligent, scalable, and patient-centred care.

methodsWe conducted a structured literature review across PubMed, Scopus, the Cochrane Library, and Web of Science, targeting English-language studies published from January 2015 to May 2025. Inclusion criteria included adult populations with a history of ACS or high cardiovascular risk, assessing interventions based on AI, telerehabilitation, or their combination. Studies are needed to report clinical, functional, behavioural, or technological outcomes. A thematic narrative synthesis was utilised.

resultsAI-enhanced telerehabilitation demonstrates potential advantages over conventional digital care in selected domains, including adaptive risk prediction, personalised exercise modulation, and adherence support. Several systems report real-time adjustment of exercise protocols, early dropout detection, and predictive analytics for rehospitalisation. AI integration may also contribute to personalised behavioural feedback and psychosocial monitoring. Nevertheless, the overall level of evidence remains preliminary and heterogeneous, with most AI-based interventions evaluated in pilot, feasibility, or modelling studies rather than large-scale randomized trials.

conclusionsThe integration of AI into telerehabilitation represents a promising evolution in post-ACS care, shifting from predominantly reactive monitoring toward more adaptive and data-driven support models. While early-phase studies suggest feasibility and potential clinical benefit, robust multicentre randomized controlled trials and cost-effectiveness analyses are required before definitive conclusions regarding superiority or widespread implementation can be drawn.

Indexed as

acute coronary syndromeartificial intelligenceexercisetelerehabilitation

Identifiers

PMID41900963
PMCPMC13027554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.