Rare Association of Bilateral Central Salzmann Nodular Degeneration and Fuchs Endothelial Dystrophy Managed by DMEK: A Case Report.

Alina Gabriela Gheorghe, Ana Maria Arghirescu, Maria Cristina Marinescu, Doina Mihaela Pop, Liliana Mary Voinea, Radu Ciuluvică

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Article in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Alina Gabriela GheorgheDepartment of Ophthalmology, Clinical Institute of Ophthalmological Emergencies "Prof. Dr. Mircea Olteanu", 010464 Bucharest, Romania.ORCID 0000-0002-9700-6112

Ana Maria ArghirescuDepartment of Ophthalmology, Clinical Institute of Ophthalmological Emergencies "Prof. Dr. Mircea Olteanu", 010464 Bucharest, Romania.ORCID 0009-0008-4802-1472

Maria Cristina MarinescuDoctoral School, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0001-8242-8809

Doina Mihaela PopFoisor Orthopaedic Hospital, 030167 Bucharest, Romania.

Liliana Mary VoineaDoctoral School, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Radu CiuluvicăDepartment of Anatomy, Faculty of Dental Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salzmann nodular degeneration is a slowly progressive, rare, degenerative disease of the cornea, usually associated with other ocular pathologies such as dry eye disease, previous ocular surgery, involving the peripheral cornea. We present the surgical management of a rare case of a patient diagnosed with Fuchs endothelial dystrophy where the Salzmann nodules present an unusual bilateral central corneal involvement and overlap the area with the most pronounced endothelial dysfunction. The patient underwent anterior superficial keratectomy, cataract surgery and Descemet membrane endothelial keratoplasty (DMEK). In vivo confocal microscopy and anterior segment optical coherence tomography have been used to monitor the morphological and structural evolution.

Indexed as

anterior segment optical coherence tomographycorneal transplantDMEKin vivo confocal microscopySalzmann corneal degenerationSalzmann nodular degeneration

Identifiers

PMID41900925

DOI10.3390/life16030406

PMCPMC13028125

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