Evidence map›Paper›PMID 41900865›Full record

ArticlePharmaceutics2026

Effects of Proglumide with Chemotherapy on the Pancreatic Tumor Microenvironment: Phase 1 PROGEM Trial.

Jill P Smith, Gakiza C Nkulikiyimana, Hong Cao, Wenqiang Chen, Bhaskar Kallakury, John Kwagyan, Anju Duttargi, Benjamin A Weinberg

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jill P SmithDepartment of Medicine, Georgetown University Medical Center, Washington, DC 20007, USA.ORCID 0000-0002-0835-4802
Gakiza C NkulikiyimanaDepartment of Biochemistry, Molecular & Cellular Biology, Georgetown University, Washington, DC 20007, USA.ORCID 0009-0000-2238-8980
Hong CaoDepartment of Medicine, Georgetown University Medical Center, Washington, DC 20007, USA.
Wenqiang ChenDepartment of Medicine, Georgetown University Medical Center, Washington, DC 20007, USA.ORCID 0009-0006-6864-9932
Bhaskar KallakuryDepartment of Pathology, MedStar Georgetown University Hospital, Washington, DC 20007, USA.ORCID 0000-0002-1298-2983
John KwagyanDepartment of Statistics, Howard University College of Medicine, Washington, DC 20059, USA.
Anju DuttargiDepartment of Oncology, Georgetown University Medical Center, Washington, DC 20007, USA.
Benjamin A WeinbergDepartment of Oncology, Georgetown University Medical Center, Washington, DC 20007, USA.ORCID 0000-0002-0408-4817

Funding

Georgetown University Medical Center Philanthropy fundNational Institute of Health P30-CA051008NCATS NIH HHS UL1-TR001409The Ruesch Center for the Cure of Gastrointestinal Cancers No number
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

chemotherapy and combination therapyfibrosispancreatic ductal adenocarcinomaproglumidetumor microenvironment

Identifiers

PMID41900865
PMCPMC13029477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.