Evidence map›Paper›PMID 41900441›Full record

ArticleMicroorganisms2026

Soft Tissue Reconstruction Does Not Compromise Infection Control in Chronic Knee Periprosthetic Joint Infection Treated with Two-Stage Exchange Arthroplasty Despite Increasing Complexity.

Carlos Mendoza Aguiló, Matías Vicente, Antonio Cano, José Antonio López Martínez, Antonio Bulla, Carles Amat, Jordi Serracanta, Pablo S Corona

Abstract read
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Postoperative wound complications and revisions in high-risk patients undergoing spine surgery with prophylactic muscle flap reconstruction: systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carlos Mendoza AguilóOrthopaedic Surgery Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain.
Matías VicenteOrthopaedic Surgery Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain.
Antonio CanoSeptic and Reconstructive Surgery Unit (UCSO), Orthopaedic Surgery Department, Vall d'Hebron University Hospital, 08035 Barcelona, Spain.
José Antonio López MartínezDepartment of Plastic Surgery and Major Burn, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain.ORCID 0000-0002-2756-8275
Antonio BullaDepartment of Plastic Surgery and Major Burn, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain.
Carles AmatOrthopaedic Surgery Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain.ORCID 0000-0002-3057-0595
Jordi SerracantaDepartment of Plastic Surgery and Major Burn, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain.ORCID 0000-0003-3268-6361
Pablo S CoronaOrthopaedic Surgery Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of soft tissue reconstruction in infection control of knee periprosthetic joint infection (PJI) treated with a two-stage exchange strategy remains controversial. This retrospective observational study analysed consecutive patients with chronic knee PJI managed with a two-stage protocol between 2010 and 2023, comparing outcomes between cases requiring flap-based soft tissue reconstruction and those achieving primary closure. A total of 118 patients with a minimum follow-up of 24 months were included. Forty patients (33.9%) required soft tissue reconstruction (STR), including 25 pedicled medial gastrocnemius flaps and 15 anterolateral thigh (ALT) microsurgical free flaps. Patients requiring STR showed greater baseline complexity, with a higher number of previous surgical procedures (3.03 vs. 2.08;

Indexed as

anterolateral thigh free flapkneemedial gastrocnemius flapmicrosurgical reconstructionorthoplastic surgeryperiprosthetic joint infectionsoft tissue reconstructiontwo-stage exchange

Identifiers

PMID41900441
PMCPMC13028888

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.