Evidence map›Paper›PMID 41900435›Full record

ArticleMicroorganisms2026

Molecular Characterization of Pathogenic Avian Reovirus Circulating in Clinically Affected Chickens in Southeastern China (2022-2023) and Its Immunosuppressive Interference with Fowl Adenovirus Serotype 4 Vaccination.

Xiaojian Chen, Yazheng Chen, Shenghua Yang, Yanhua Xu, Xuesong Li, Zhanxin Wang, Lijuan Yin, Wencheng Lin

Abstract read
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaojian ChenCollege of Animal Science, South China Agricultural University, Guangzhou 510642, China.
Yazheng ChenCollege of Animal Science, South China Agricultural University, Guangzhou 510642, China.
Shenghua YangWen's Foodstuffs Group Co., Ltd., Yunfu 527400, China.
Yanhua XuWen's Foodstuffs Group Co., Ltd., Yunfu 527400, China.
Xuesong LiWen's Foodstuffs Group Co., Ltd., Yunfu 527400, China.
Zhanxin WangWen's Foodstuffs Group Co., Ltd., Yunfu 527400, China.
Lijuan YinWen's Foodstuffs Group Co., Ltd., Yunfu 527400, China.
Wencheng LinCollege of Animal Science, South China Agricultural University, Guangzhou 510642, China.

Funding

the Fourth Round of Guangdong Provincial Modern Agricultural Industry Technology System Innovation Team Construction Project 2024CXTD15the National Key R&D Program of China 2023YFD1301800the Science and Technology Plan Program of Guangdong Province 2023B1212070018the Science and Technology Plan Program of Yunfu city 2024020101the Science and Technology Plan Program of Yunfu city 2024090301the Science and Technology Plan Program of Yunfu city YF2025NYRC03
6 · The paper itself

Abstract

Avian reovirus (ARV) is a ubiquitous pathogen in commercial poultry, traditionally associated with viral arthritis, malabsorption syndrome, and growth retardation. In recent years, the rapid genetic diversification of ARV has raised increasing concerns regarding vaccine mismatch, immune dysregulation, and complex disease outcomes in vaccinated flocks. In this study, an integrated investigation combining large-scale field surveillance, molecular characterization, and controlled animal experiments was conducted to elucidate the epidemiological features of ARV and its impact on heterologous vaccine-induced protection. Epidemiological surveillance revealed widespread ARV circulation in commercial poultry flocks, with marked genetic divergence between contemporary field isolates and classical vaccine strains. Phylogenetic analysis based on the

Indexed as

avian reovirusfowl adenovirus serotype 4immunosuppressionmolecular epidemiologyvaccine interference

Identifiers

PMID41900435
PMCPMC13029336

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.