ArticleMicroorganisms2026
Rapid Diagnostic Testing in Bloodstream Infections: A Retrospective Clinical and Economic Evaluation from a University Hospital in Bulgaria.
Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Rapid diagnostic tests enable earlier pathogen identification in bloodstream infections compared with conventional culture-based methods and may improve clinical and economic outcomes, particularly when integrated with antimicrobial stewardship programs. Evidence suggests that while mortality benefits are context-dependent, rapid diagnostics can optimize antibiotic use and hospital resource allocation. The present study aimed to evaluate the clinical and economic impact of rapid diagnostic approaches compared with conventional microbiological culture in patients with confirmed bacteremia or fungemia hospitalized in a tertiary care setting in Bulgaria. A retrospective observational study was conducted between January 2015 and August 2020 at University Hospital "St. George," Plovdiv. A total of 115 patients with confirmed bacteremia or fungemia were included and allocated to either a rapid diagnostic testing group (
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