Association Between Gut Microbiota and HIV Infection Risk: Insights from Mendelian Randomization and 16S rRNA Amplicon Sequencing.

Jiali Chen, Tingting Yuan, Ji Pu, Ying Li, Han Zheng, Jing Yang, Jianguo Xu

Abstract read

In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiali ChenSchool of Medicine, Research Institute of Public Health, Nankai University, Tianjin 300071, China.ORCID 0000-0002-2386-8078

Tingting YuanSchool of Medicine, Research Institute of Public Health, Nankai University, Tianjin 300071, China.ORCID 0009-0005-2498-8193

Ji PuNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.

Ying LiSchool of Medicine, Research Institute of Public Health, Nankai University, Tianjin 300071, China.

Han ZhengNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.

Jing YangNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.

Jianguo XuSchool of Medicine, Research Institute of Public Health, Nankai University, Tianjin 300071, China.

Funding

Comprehensive Innovation Capability Support of Intelligent Tracking and Forecasting for Infectious Diseases No. 102393240020020000004National Science and Technology Major Project 2025ZD01900110

6 · The paper itself

Abstract

Observational evidence links gut microbiota (GM) dysbiosis to HIV infection; however, the causal relationship between them has not been established. Mendelian randomization (MR) and 16S rRNA gene sequencing analyses were performed to identify gut microbial taxa associated with HIV infection risk. MR analysis results identified 18 gut microbial taxa associated with HIV infection (

Indexed as

causalitygut microbiotaHIVmendelian randomization

Identifiers

PMID41900426

DOI10.3390/microorganisms14030667

PMCPMC13029254

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.