Evidence map›Paper›PMID 41900396›Full record

ReviewMicroorganisms2026

KSHV and Human Diseases: Beyond KS, PEL and MCD.

Caroline Grace Firmin, Lu Dai, Zhiqiang Qin

Abstract readReview
In one paragraph

Review in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Caroline Grace FirminDepartment of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR 72205, USA.
Lu DaiDepartment of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR 72205, USA.
Zhiqiang QinDepartment of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR 72205, USA.ORCID 0000-0002-9905-1275

Funding

Development of O’PROTACs-based degraders targeting an oncogenic viral proteinR21AI186566 · NIAID · UNIV OF ARKANSAS FOR MED SCIS · PI Lu Dai · 2025 to 2026
$415k
Role of Macrophage Migration Inhibitory Factor (MIF) in KSHV-associated MalignanciesR03DE034653 · NIDCR · UNIV OF ARKANSAS FOR MED SCIS · PI DAI, LU · 2025 to 2025
$306k
National Institute of Health R21AI186566, R03DE034653NIAID NIH HHS R21 AI186566NIDCR NIH HHS R03 DE034653
6 · The paper itself

Abstract

Kaposi's Sarcoma-associated herpesvirus (KSHV) has been etiologically linked to several human cancers, including Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman's disease (MCD). However, recent studies suggest that KSHV infection may also be associated with the development of other diseases or increased risks, such as KSHV inflammatory cytokine syndrome (KICS), diabetes, malaria, heart disease, and other cancers. In this review, we summarize these findings from clinical observations, epidemiological studies or laboratory research, though more studies are needed in these emerging areas. We believe that this work will enhance our understanding of the molecular mechanisms underlying KSHV pathogenesis and contribute to improving treatments for related human diseases.

Indexed as

cervical cancerdiabetes mellitusheart diseaseKICSKSHVmalariaosteosarcomaprostate cancer

Identifiers

PMID41900396
PMCPMC13029099

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.